Publications by authors named "Gabriele R"
Article Synopsis
- - The study analyzed data from over 1.3 million cancer surgery patients in Italy to explore how adherence to cancer screening programs affected early cancer diagnoses before and during the COVID-19 pandemic (2015-2022).
- - Findings showed a significant 45% drop in surgeries during the pandemic, particularly for screenable cancers like breast, colorectal, and cervical cancer, along with a 33.8% reduction in screenings in the first year of COVID-19.
- - The research highlighted that adherence to screening was lower among individuals in rural areas, with low socio-economic status, and those with less education, while organized free screening programs helped reduce these disparities.
Introduction And Importance: Metastatic cancer of the umbilicus is an uncommon and rare presentation.
Case Presentation: Our interest for the clinical outcomes of umbilical metastases from colon cancer arose after a 60-years old lady with ulcerated umbilical lesion came to our clinic. She was seen in several other clinics, and the diagnoses of infection of the umbilical region and/or of umbilical hernia were made.
Background: The aim of our study was to determine a correlation between decrease of levels of atmospheric pollution (as determined by air levels of Particulate Matters with a diameter equal or less to 2.5 microns) and reduced number of hospital admissions and operations for patients with common cardiovascular diseases in Italy.
Methods: We correlated number of hospital admissions and cardiovascular operations and atmospheric levels of PM.
Women with acute and chronic myocardial ischaemia have worse early results after PTCA and CABG, but better 1-year results.
Eur Heart J Qual Care Clin Outcomes
December 2024
Introduction: Familial Alzheimer's disease (fAD) is heterogeneous in terms of age at onset and clinical presentation. A greater understanding of the pathogenicity of fAD variants and how these contribute to heterogeneity will enhance our understanding of the mechanisms of AD more widely.
Methods: To determine the pathogenicity of the unclassified PSEN1 P436S mutation, we studied an expanded kindred of eight affected individuals, with magnetic resonance imaging (MRI) (two individuals), patient-derived induced pluripotent stem cell (iPSC) models (two donors), and post-mortem histology (one donor).
Background: The unexpected virulence of the COVID19 pandemic brought to significant changes of generally accepted therapeutic approaches. The consequences of these changes were difficult to define during the pandemic period.
Methods: We analyzed the National Registries including 97% of hospital admissions in Italy, regarding data describing number of operations for aortic valve implantation or repair, carotid and coronary revascularization, AAA repair, and lower limb arterial reconstruction performed in the period 2015 to 2019 and in the pandemic years 2020, 2021, and 2022.
Background: the aim of our study was to analyze exposure of the general population to established risk factors for cardiovascular disease (CVD), which might have determined the trend towards increased mortality rates related with CVD from 2015 to 2019 in USA.
Material And Methods: We Analyzed epidemiological of data from the US National Health and Nutrition Examination Survey and from the European Health Interview Survey to determine trends for exposure to several established risk factors for CVD from 2000 to 2018-2019. Trends of prevalence of obesity, arterial hypertension, cigarettes smoking, high cholesterol level, diabetes in the period 2000 to 2018-2019 in USA were correlated with age adjusted mortality and burden related with CVD.
Background: In Europe Cardio Vascular Disease (CVD) mortality rates decreased significantly in the last 25 years, with less decline in the last 5 years. The aim of our study was to analyze trends of risk factors which may explain plateauing of CVD mortality rates in the period 2015-2019 in Europe.
Methods: We analyzed data from the Global Burden Disease and EUROSTAT concerning trends of CVD mortality rates for 25 European countries and simultaneous changes of exposure to risk factors of the population RESULTS: CVD related mortality decreased significantly in the analyzed countries in the period 2000-2015; in the period 2015-2019 there was a trend towards plateauing of CVD related mortality rates, which was associated with an increased exposure to several established risk factors including cigarette smoking, obesity and arterial hypertension.
Background: In this study we correlated changes of risk factors for cardiovascular diseases with trends of age standardized mortality rates and burden for aortic aneurysms and dissections.
Methods: We analyzed data from the Global Burden of Diseases and EUROSTAT.
Findings: There was a significant increase of expenditure for health from 1980 and 2019.