Publications by authors named "Gabriele Marchetti"

Article Synopsis
  • - Disseminated non-tuberculous mycobacterial (NTM) infections can severely impact patients with weakened immune systems, potentially leading to serious conditions like hemophagocytic syndrome (HPS) if not diagnosed quickly.
  • - A case study involved a 63-year-old woman with suspected autoimmune disease who met the criteria for HPS, with Mycobacterium avium isolated from multiple sources including blood and bone marrow.
  • - For better treatment outcomes in immunocompromised patients, early detection of mycobacterial infections and HPS, along with appropriate lab testing for drug resistance, is crucial.
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We emulated a hypothetical target trial in which hematological subjects cared at the University Hospital of Pisa (Italy) received or not SARS-CoV-2 prophylaxis with tixagevimab/cilgavimab. Subjects who received prophylaxis (cases) were compared to those who did not (controls). The main outcome was SARS-CoV-2 infection in the subsequent 6 months.

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Introduction: Different antivirals are available for the treatment of outpatients with COVID-19. Our aim was to describe a real-world experience of outpatient management of COVID-19 subjects at high risk of progression.

Methods: This prospective observational study conducted in the University Hospital of Pisa (January 2022-July 2022) included consecutive COVID-19 outpatients with at least one risk factor for disease progression.

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