The influence of filler load in 3D printing resin-based composites.

Objective: To evaluate the influence of the barium glass (BG) filler in 3D printing resin-based composites for restorative structures.

Methods: Experimental 3D printing resin-based composites were formulated with UDMA 70%wt, Bis-EMA 20%wt, and TEGDMA 10%wt. Photoinitiators TPO and DFI (2%wt) were used.

In vitro development and optimization of cell-laden injectable bioprinted gelatin methacryloyl (GelMA) microgels mineralized on the nanoscale.

Bone defects may occur in different sizes and shapes due to trauma, infections, and cancer resection. Autografts are still considered the primary treatment choice for bone regeneration. However, they are hard to source and often create donor-site morbidity.

Modulation of blood redox status by the progression of induced apical periodontitis in rats.

This study aimed to investigate if apical periodontitis in different periods changes systemic levels of the antioxidant and pro-oxidant parameters in Wistar rats. Twenty-four rats were randomly allocated into healthy animals, apical periodontitis at 14 days (AP14) and apical periodontitis at 28 days (AP28). The first mandibular molars were accessed in the AP groups, and the pulp chamber was exposed to the oral environment, inducing the apical lesion.

Controlled drug delivery from metronidazole-containing bioactive endodontic cements.

Objectives: This study aims to formulate metronidazole liquid nanocapsules (MTZ) and evaluate their effect on the physicochemical and biological properties of calcium silicate-based bioactive endodontic cements, in vitro.

Methods: A MTZ suspension was formulated by deposition of the preformed polymer and characterized by laser diffraction and high-performance liquid chromatography (HPLC). Calcium silicate (CS) was mixed with a radiopaque agent (calcium tungstate - CaWO), at 10 wt%, to produce the cement powder.

Niobium-containing bioactive glasses modulate alkaline phosphatase activity during bone repair.

This study aimed to evaluate the pre-clinical behavior of niobium-containing bioactive glasses (BAGNb) by their ability to promote bone repair and regulate alkaline phosphatase (ALP) levels in an animal model. BAGNbs were produced as powders and as scaffolds and surgically implanted in the femur of male rats (Wistar lineage n = 10). Glasses without Nb (BAG) were produced and implanted as well.

Antibacterial Effect of Triazine in Barrier Membranes with Therapeutic Activity for Guided Bone Regeneration.

Objective: This study aimed to develop polymer-based barrier membranes based on poly(butylene-adipate-co-terephthalate) (PBAT) with the addition of 1,3,5-triacriloilhexahydro-1,3,5-triazine (TAT). Materials and Methods: Polymeric solutions were used to produce membranes with 5 wt% and 10 wt% of TAT by solvent casting. Membranes without the addition of TAT were used as controls.

In utero and lactational exposure to methylmercury elicits physical-chemical and morphological damages in the alveolar bone of offspring rats: The first toxicological findings.

Methylmercury (MeHg) is the most common organic form of mercury (Hg) that humans are exposed and is considered an environmental pollutant. Several populations that live in endemic regions of MeHg exposure are subject to the toxicant for long periods, including pregnant women and children, causing damage to several organs during early periods of development. Alveolar bone is an essential structure for the oral cavity, responsible for supporting teeth and masticatory forces.

Non-thermal plasma for surface treatment of inorganic fillers added to resin-based cements.

Objectives: This study aims to evaluate the effect of non-thermal plasma (NTP) surface treatment in two composite inorganic fillers and evaluate their impact on the chemical-mechanical properties and bond strength ability of experimental resin cements.

Materials And Methods: Ytterbium fluoride (YF) and barium silicate glass (BS) were characterized and submitted to different surface treatments: non-thermal plasma (NTP); non-thermal plasma and 3-(trimethoxysilyl) propyl methacrylate silanization; and 3-(trimethoxysilyl) propyl methacrylate silanization. Untreated fillers were used as a control.

Long-term exposure to low doses of aluminum affects mineral content and microarchitecture of rats alveolar bone.

Aluminum (Al) is one of the most found elements in nature in many forms, and human exposure can be quite common. Therefore, it is important to investigate the effects of exposure to Al mainly at low doses and for a prolonged period, in order to simulate human exposure in the periodontium, an important structure for support and protection of the teeth. This investigation aimed to study the aluminum chloride (AlCl) toxicological effects in the mineral composition and micromorphology of the alveolar bone of rats.

Niobium silicate as a filler for an experimental photopolymerizable luting agent.

Purpose: To synthesize niobium silicate particles (SiNb) and incorporate into resin-based luting agents.

Methods: SiNb particles were synthesized and characterized by x-ray diffraction, FTIR spectroscopy, particle size, and specific surface area. Luting agents were formulated with 50 wt% BisGMA, 30 wt% TEGDMA and 20 wt% UDMA.

Prolonged caffeine intake decreases alveolar bone damage induced by binge-like ethanol consumption in adolescent female rats.

Ethanol consumption has been reported to negatively impact on periodontal disease. In particular, oral cavity disorders occur upon ethanol exposure during adolescence, a life period associated with particular patterns of short and intense ('binge-like') ethanol consumption that is most deleterious to oral health. The hazardous central effects of ethanol have been linked to the overfunction of adenosine receptors, which are antagonized by caffeine, a bioactive substance present in numerous natural nutrients, which can also modify bone metabolism.

Evaluation of the Physicochemical and Antibacterial Properties of Experimental Adhesives Doped with Lithium Niobate.

The aim of the present study was to formulate dental adhesives with different concentrations of LiNbO and to evaluate their physicochemical and antibacterial properties. A dental adhesive was formulated using methacrylate monomers and photoinitiators and used as a control filler-free group. Subsequently, three experimental adhesives doped with LiNbO at different concentrations (1 wt.

Quaternary ammonium compound as antimicrobial agent in resin-based sealants.

Objectives: The aim of this study was to evaluate the influence of [2-(methacryloyloxy)ethyl] trimethylammonium chloride (METAC) in the physico-chemical properties, antibacterial activity and cytotoxicity of an experimental resin-based sealant.

Materials And Methods: An experimental resin-based sealant was formulated with dimethacrylates and a photoinitiator system. METAC was added at 2.

Ionic liquid as antibacterial agent for an experimental orthodontic adhesive.

Objective: The aim of this study was to formulate and evaluate experimental orthodontic adhesives with different concentrations of 1-n-butyl-3-methylimidazoilium bis(trifluoromethanesulfonyl)imide (BMIM.NTf).

Methods: The experimental orthodontic adhesives were formulated with methacrylate monomers, photoinitiators and silica colloidal.

Boron Nitride Nanotubes as Filler for Resin-Based Dental Sealants.

The aim of this study was to evaluate the influence of boron-nitride nanotubes (BNNTs) on the properties of resin-based light-curing dental sealants (RBSs) when incorporated at different concentration. RBSs were formulated using methacrylate monomers (90 wt.% TEGDMA, 10 wt.

Halloysite nanotubes loaded with alkyl trimethyl ammonium bromide as antibacterial agent for root canal sealers.

Objective: This study aimed at evaluating the effects of experimental endodontic sealers containing halloysite nanotubes (HNT) doped with alkyl trimethyl ammonium bromide (ATAB).

Methods: An experimental dual-cure resin sealer was formulated and used as control material. This resin was also filled with ATAB and HNT at different ratios (GATAB:HNT 1:1; 1:2; 2:1) generate three experimental resin sealers.

Physical and mechanical properties of dual functional cements-an in vitro study.

Objectives: The aim of this study was to evaluate the physical and mechanical properties of different dual functional cements.

Materials And Methods: Three dual functional cements (Allcem Core (FGM), Rebilda DC (VOCO), and LuxaCore Z (DMG)), a luting resin cement (Rely X ARC (3 M ESPE)), and a Core Buildup composite resin GrandioSo (VOCO) were used. Flexural strength (n = 10) and film thickness (n = 6) were evaluated according to ISO 4049:2009.

Influence of the addition of microsphere load amoxicillin in the physical, chemical and biological properties of an experimental endodontic sealer.

Aim: To develop an endodontic sealer with amoxicillin-loaded microsphere and to evaluate its properties.

Methods: Experimental sealer was obtained by mixing 70wt% UDMA, 15wt% GDMA and 15wt% BISEMA. In addition, CQ, DHEPT and PB were incorporated at 1 mol% and 0.