Introduction: The purpose of this study was to determine the position of the apical foramen (AF) in relation to root surfaces of human permanent teeth using cone-beam computed tomographic (CBCT) imaging and novel advanced imaging analysis software (e-Vol DX; CDT Software, Bauru, SP, Brazil).
Methods: The AF position was determined on CBCT scans viewed and analyzed using e-Vol DX of 1400 teeth (422 patients) according to the root surface as follows: buccal, mesiobuccal, mesial, mesiolingual/palatal, lingual/palatal, distolingual/palatal, distal, distobuccal, and central. Categoric variables were described as frequencies and percentages.