Unconventional and conventional Pickering emulsions: Perspectives and challenges in skin applications.

Pickering emulsions are free from molecular and classical surfactants and are stabilized by solid particles, creating long-term stability against emulsion coalescence. Additionally, these emulsions are both environmentally and skin-friendly, creating new and unexplored sensorial perceptions. Although the literature mostly describes conventional emulsions (oil-in-water), there are unconventional emulsions (multiple, oil-in-oil and water-in-water) with excellent prospects and challenges in skin application as oil-free systems, permeation enhancers and topical drug delivery agents, with various possibilities in pharmaceutical and cosmetic products.

Modulation of Epidermal Growth Factor Release by Biopolymer-Coated Liposomes.

This work describes the development of polysaccharide-coated liposomes to modulate the delivery of epidermal growth factor (EGF), with the aim to produce different EGF release profiles depending on the milieu of infected wounds. For this purpose, cationic liposomes were coated with one layer of sodium alginate (ALG) followed by one layer of chitosan (CHI) using the layer-by-layer (LbL) technique. The coated liposomes exhibited apparent hydrodynamic diameters of 278 ± 36 and 216 ± 96 nm for Lip-ALG and Lip-ALG-CHI, respectively.

Development, characterization and antimicrobial activity of sodium dodecyl sulfate-polysaccharides capsules containing eugenol.

This work describes the production of polysaccharide multilayer capsules to control the release of Eugenol (Eug) and enabling its use as an antimicrobial agent. For this propose, oil-in-water nanoemulsions of sodium dodecyl sulfate were coated with alternating depositions of chitosan and carboxymethylcellulose using the Layer-by-Layer (LbL) technique, resulting in capsules containing 1-5 layers. The average size ranged from 188 ± 30 (LbL) to 1415 ± 517 nm (LbL).