Publications by authors named "Gabriela M Garcia"

The infralimbic (IL) division of the medial prefrontal cortex (mPFC) is a crucial site for the extinction of conditioned fear memories in rodents. Recent work suggests that neuronal plasticity in the IL that occurs during (or soon after) fear conditioning enables subsequent IL-dependent extinction learning. We therefore hypothesized that pharmacological activation of the IL after fear conditioning would promote the extinction of conditioned fear.

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Article Synopsis
  • The infralimbic (IL) division of the medial prefrontal cortex plays a vital role in extinguishing conditioned fear memories in rodents, with important neuronal changes occurring during fear conditioning.
  • Researchers hypothesized that activating the IL with a GABA receptor antagonist, picrotoxin, after fear conditioning could enhance the process of fear extinction.
  • Experiments showed that picrotoxin injections significantly reduced conditioned freezing responses in rats up to two weeks later, indicating that the IL may hold an inhibitory memory necessary for suppressing fear.
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Background: Efficient deconstruction and bioconversion of solids at high mass loadings is necessary to produce industrially relevant titers of biofuels from lignocellulosic biomass. To date, only a few studies have investigated the effect of solids loadings on microorganisms of interest for consolidated bioprocessing. Here, the effects that various switchgrass loadings have on solubilization and bioconversion are investigated.

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In clinical practice, nurses perform different activities that exceed direct care of patients, and influence workload and time administration among different tasks. When implementing changes in an electronic nursing record, it is important to measure how it affects the time committed to documentation. The objective of this study was to determine the time dedicated to different activities, including those related to electronic documentation prior to implementing a redesigned nurse chart in an Electronic Health Record at the Hospital Italiano de Buenos Aires.

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