Publications by authors named "Gabriela Guimaraes Vieira"

Article Synopsis
  • Pediatric cardiac tumors are uncommon, with the majority being benign, and cardiac fibroma is notably the second most common type after rhabdomyoma.
  • A case of a 5-month-old boy with acute viral bronchiolitis revealed incidental findings of a cardiac fibroma via various diagnostic tests, including echocardiogram and cardiac catheterization, leading to its confirmation.
  • Treatment typically involves surgery or heart transplantation, especially for cases with significant dysfunction, and accurate characterization of the tumor is crucial for determining the best therapeutic strategy.
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Objective: To assess intra- and interobserver agreement among non-expert pathologists in identifying features of the eosinophilic esophagitis histologic scoring system (EoEHSS) in pediatric patients.

Patients And Methods: The authors used 50 slides from patients (aged 1-15 years; 72% male) with EoE. EoEHSS evaluates eosinophilic inflammation and other features including epithelial basal zone hyperplasia, eosinophilic abscesses, eosinophil surface layering, dilated intercellular spaces, surface epithelial alteration, dyskeratotic epithelial cells, and lamina propria fibrosis.

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Objective: To compare endoscopic and histologic features of pediatric patients with eosinophilic esophagitis (EoE) responding to proton pump inhibitor (PPI) to those not responding to PPI.

Methods: Endoscopic reports and photographs of patients with symptoms of esophageal dysfunction and ≥15 eosinophils per high-powered field (eos/hpf) in esophageal biopsies prior to PPI trial were reviewed. Patients were classified as responsive to PPI (PPIREoE) or non-responsive to PPI (PPINREoE) according to response totreatment (<15 eos/hpf) at second endoscopy after 8 weeks.

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