Acute responses of hemodynamic and oxidative stress parameters to aerobic exercise with blood flow restriction in hypertensive elderly women.

Systemic arterial hypertension has been associated with the majority deaths from cardiovascular disease, especially among the elderly population, and the imbalance between antioxidant and pro-oxidants has been associated with hypertension. This study analyzed the acute responses of cardiorespiratory and oxidative stress parameters to low intensity aerobic exercise (LIAE) with blood flow restriction (BFR) in hypertensive elderly women. The experimental group consisted of 16 hypertensive women (67.

Ebi3 Prevents Induced Myocarditis by Dampening IFN-γ-Driven Inflammation.

The identification of anti-inflammatory mediators can reveal important targetable molecules capable of counterbalancing -induced myocarditis. Composed of Ebi3 and IL-27p28 subunits, IL-27 is produced by myeloid cells and is able to suppress inflammation by inducing IL-10-producing Tr1 cells, thus emerging as a potential candidate to ameliorate cardiac inflammation induced by . Although IL-27 has been extensively characterized as a suppressive cytokine that prevents liver immunopathogenesis after infection, the mechanisms underlying its effects on -induced myocarditis remain largely unknown.

Detection of antibodies against Paracoccidioides brasiliensis in free-range domestic pigs (Sus scrofa).

Paracoccidioidomycosis, caused by the thermodimorphic fungus Paracoccidioides brasiliensis, is a human systemic mycosis prevalent in Latin America. Paracoccidioidomycosis affects mainly male rural workers, causing granulomatous lesions in several organs such as the lungs, liver and spleen. The participation of other animal species in the fungus epidemiology is not well understood.

Paracoccidioides brasiliensis infection in domestic rabbits (Oryctolagus cuniculus).

The objective of this study was to evaluate the infection of domestic rabbits by Paracoccidioides brasiliensis. Initially two rabbits were experimentally infected with P. brasiliensis and the humoral immune response was evaluated by ELISA using gp43 as antigen.