Publications by authors named "Gabriela Cunha de Franca"
Objective: To assess a comparative analysis of the ROX index, Wood-Downes-Ferrés score (WDF), p-ROXI, and the SpO2/FiO2 ratio as predictors of high-flow nasal cannula (HFNC) failure in children hospitalized for bronchiolitis.
Methods: Data were extracted from the clinical trial "Comparison between HFNC and NIV in children with acute respiratory failure caused by bronchiolitis" conducted at a tertiary Brazilian hospital (Emergency Department and PICU). The inclusion criteria were children under 2 years of age admitted for bronchiolitis who developed mild to moderate respiratory distress and were eligible for HFNC therapy.
"Comparison between high-flow nasal cannula (HFNC) therapy and noninvasive ventilation (NIV) in children with acute respiratory failure by bronchiolitis: a randomized controlled trial".
Ana Carolina Etrusco Zaroni Santos Carolina Marques Caiado Alessandra Geisler Daud Lopes Gabriela Cunha de França Ana Karolina Antunes Eisen
BMC Pediatr
September 2024
Article Synopsis
- - The study aimed to determine if high-flow nasal cannula (HFNC) therapy is at least as effective as noninvasive ventilation (NIV/BiPAP) for treating bronchiolitis-related respiratory failure in children under 2 years old.
- - Conducted in a Brazilian hospital, the trial involved 126 children in each treatment group, with assessments of their health and treatment outcomes, including the need for intubation and length of hospital stay.
- - Results showed a lower intubation rate in the HFNC group (23%) compared to the NIV group (29%), and while the difference was not statistically significant, HFNC therapy resulted in lower sedation needs and hospital stays, indicating it could be a