Publications by authors named "Gabriela Costa Bernardes"
Respir Physiol Neurobiol
December 2022
Article Synopsis
- Oxygen therapy can help prevent or treat low oxygen levels (hypoxia), but too much oxygen (hyperoxia) can harm the brain.
- A study on male Wistar rats found that those exposed to high oxygen levels (40% and 60% FIO) experienced increased oxidative stress and mitochondrial dysfunction compared to a control group receiving normal oxygen levels (21% FIO).
- The most affected brain regions, such as the hippocampus and cerebellum, showed signs of cellular damage, like lipid oxidation and altered enzyme activities, indicating negative effects from hyperoxia.
