Publications by authors named "Gabriela Carvalho Machado"

Article Synopsis
  • The study aims to explore how transient evoked otoacoustic emissions (TEOAE) signals in neonates and infants with congenital hypothyroidism are related to their clinical and lab results.
  • It involved comparing TEOAE amplitudes between 22 infants with congenital hypothyroidism and 22 without, aged 0-12 months, using statistical tests.
  • Results showed no significant differences in TEOAE amplitudes between the groups, but a connection was found between TEOAE amplitudes and levels of thyroid hormones like TSH and T4, suggesting these hormones may affect hearing.
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Purpose: To verify evidence of subclinical alterations through self-reported participation restrictions in normal hearing individuals and congenital hypothyroidism patients.

Methods: An analytical, quantitative, cross-sectional exploratory study with a 1:1 ratio, consisting of a convenience sample of 86 normal hearing individuals with (n = 42) and without (n = 44) congenital hypothyroidism diagnosis. All participants underwent tonal and speech audiometry, immitance and distortion product otoacoustic emissions.

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Introduction: The investigation of amplitudes of otoacoustic emissions in congenital hypothyroidism can provide information on cochlear function with more sensibility, when compared to other methods of auditory evaluation.

Aim: To investigate cochlear function through the amplitude of distortion product otoacoustic emissions in individuals with congenital hypothyroidism and to correlate with clinical aspects.

Methods: An exploratory, analytical, cross-sectional study with a convenience sample, composed of 50 individuals with congenital hypothyroidism and a group of 42 individuals without the disease, mean age of 8.

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Objective: To investigate the presence of central auditory processing disorder symptoms in children with congenital hypothyroidism.

Methods: An exploratory, descriptive, cross-sectional study of 112 patients with congenital hypothyroidism aged ≥5 years old. An interview was held with the parents/caregivers at the time of the medical consultation.

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Endocochlear, retrocochlear and/or central origin hearing damage may be related to the absence of appropriate levels of thyroid hormone during morphogenesis and/or auditory system development. Hearing disorders related to the thyroid are not well studied, despite speculation on the pathophysiological mechanisms. The objective of this review was to characterize the main pathophysiological mechanisms of congenital hypothyroidism and to evaluate the relationship with central and peripheral hearing disorders.

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