Publications by authors named "Gabriela Arreola-Ramirez"
Article Synopsis
- The report describes four cases of serious congenital cytomegalovirus (CMV) infections diagnosed after birth, primarily through cerebrospinal fluid and blood tests, along with placenta analyses.
- All infants were premature, and factors like younger maternal age and low-income background were linked to the cases.
- Major complications included hydrocephalus and thrombocytopenia, with two children dying and one facing severe neurological issues, highlighting the importance of antenatal CMV screening even in areas with high seropositivity like Mexico.
Over the last 20 years, the incidence of vertical HIV transmission has decreased from 25%-42% to less than 1%. Although there are no signs of infection, the health of HIV-exposed uninfected (HEU) infants is notoriously affected during the first months of life, with opportunistic infections being the most common disease. Some studies have reported effects on the vertical transfer of antibodies, but little is known about the subclass distribution of these antibodies.
View Article and Find Full Text PDFPreterm neonates are at high risk of infectious and inflammatory diseases which require antibiotic treatment. Antibiotics influence neonatal gut microbiome development, and intestinal dysbiosis has been associated with delayed gastrointestinal transit. Neonates who take less time to pass meconium have a better tolerance to enteral feeding.
View Article and Find Full Text PDFPassive transplacental immunity is crucial for neonatal protection from infections. Data on the correlation between neonatal immunity to SARS-CoV-2 and protection from adverse outcomes is scarce. This work aimed to describe neonatal seropositivity in the context of maternal SARS-CoV-2 infection, seropositivity, and neonatal outcomes.
View Article and Find Full Text PDFIntroduction: HIV-exposed uninfected (HEU) newborns suffer from higher risks of opportunistic infections during the first months of life compared to HIV-unexposed uninfected (HUU) newborns. Alterations in thymic mass, amounts of T helper (Th) cells, T-cell receptor diversity, and activation markers have been found in HEU newborns, suggesting alterations in T cell ontogeny and differentiation. However, little is known about the ability of these cells to produce specialized Th responses from CD4 T cells.
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