Publications by authors named "Gabriel Watson"
Background: Vascular calcification and increased extracellular matrix (ECM) stiffness are hallmarks of vascular aging. Sox9 (SRY-box transcription factor 9) has been implicated in vascular smooth muscle cell (VSMC) osteo/chondrogenic conversion; however, its relationship with aging and calcification has not been studied.
Methods: Immunohistochemistry was performed on human aortic samples from young and aged patients.
Purpose: To investigate predictors of conduct problem (CP) treatment in an outpatient child psychiatry clinic.
Design And Methods: Medical records (N = 78) of youth with CPs (71% male; mean age = 9.9 years) were analyzed to determine how treatment history, race, gender, travel distance, aggression symptoms, internalizing disorder symptoms, and age of diagnosis influenced initial treatment decisions.
Current state of evidence for medication treatment of preschool internalizing disorders.
ScientificWorldJournal
December 2014
Article Synopsis
- - Psychiatrists are prescribing psychotropic medications off-label to preschoolers with internalizing disorders like anxiety and depression, but research on this practice is limited and relies on weak methodologies.
- - A systematic review identified 11 studies addressing the effectiveness of these medications in children aged 2-5, highlighting the need for better research and understanding in this area.
- - The review emphasizes the importance of mental health practitioners being informed about the current evidence, and suggests monitoring strategies for assessing the costs and benefits of medication for young children, while calling for more research in this field.