Publications by authors named "Gabriel Strandberg"
Introduction: In kidney transplantation (KT), the role of the intravascular innate immune system (IIIS) in response to ischemia-reperfusion injury (IRI) is not well-understood. Here, we studied parallel changes in the generation of key activation products of the proteolytic cascade systems of the IIIS following living donor (LD) and deceased donor (DD) transplantation and evaluated potential associations with clinical outcomes.
Methods: In a cohort study, 63 patients undergoing LD ( = 26) and DD ( = 37) transplantation were prospectively included.
The pig is commonly used in renal transplantation studies since the porcine kidney resembles the human kidney. To meet the requirements of intense caretaking and examination without stress, a 2-week socialisation and training programme was developed. Conventional cross-breed pigs ( = 36) with high health status were trained for 15 min/day in a four-step training programme before kidney transplantation.
View Article and Find Full Text PDFBackground: Over the past decades, the focus on the regenerative properties of platelets (PLTs) has intensified and many PLT-derived growth factors are readily used in medical settings. A general lack of standardization in the preparation of these growth factors remains, however, and this study therefore examines the dynamics of growth factors throughout the freeze-thaw procedure.
Study Design And Methods: Plateletpheresis (PA) and PLT-poor plasma (PPP) samples were collected from 10 healthy donors.
Background: Platelet lysate is a readily available source of growth factors, and other mediators, which has been used in a variety of clinical applications. However, the product remains poorly standardized and the present investigation evaluates the composition of platelet lysate obtained from either fresh or stored pathogen-inactivated platelet units.
Materials And Methods: Platelet pooled units (n = 10) were obtained from healthy blood donors and tested according to standard procedures.