Integrating fNIRS and machine learning: shedding light on Parkinson's disease detection.

The purpose of this research is to introduce an approach to assist the diagnosis of Parkinson's disease (PD) by classifying (fNIRS) studies as PD positive or negative. fNIRS is a non-invasive optical signal modality that conveys the brain's hemodynamic response, specifically changes in blood oxygenation in the cerebral cortex; and its potential as a tool to assist PD detection deserves to be explored since it is non-invasive and cost-effective as opposed to other neuroimaging modalities. Besides the integration of fNIRS and machine learning, a contribution of this work is that various approaches were implemented and tested to find the implementation that achieves the highest performance.

Causal Forest Machine Learning Analysis of Parkinson's Disease in Resting-State Functional Magnetic Resonance Imaging.

In recent years, Artificial Intelligence has been used to assist healthcare professionals in detecting and diagnosing neurodegenerative diseases. In this study, we propose a methodology to analyze functional Magnetic Resonance Imaging signals and perform classification between Parkinson's disease patients and healthy participants using Machine Learning algorithms. In addition, the proposed approach provides insights into the brain regions affected by the disease.

Classification of PPMI MRI scans with voxel-based morphometry and machine learning to assist in the diagnosis of Parkinson's disease.

Background And Objectives: Qualitative and quantitative analyses of Magnetic Resonance Imaging (MRI) scans are carried out to study and understand Parkinson's Disease, the second most common neurodegenerative disorder in people at their 60's. Some quantitative analyses are based on the application of voxel-based morphometry (VBM) on magnetic resonance images to determine the regions of interest, within gray matter, where there is a loss of the nerve cells that generate dopamine. This loss of dopamine is indicative of Parkinson's disease.