Atorvastatin inhibits osteoclastogenesis and arrests tooth movement.

Introduction: In addition to their cholesterol-lowering effects, the statin class of drugs appears to enhance osteogenesis and suppress bone resorption, which could be a clinical concern during orthodontic treatment. In this animal study, we aimed to determine whether atorvastatin (ATV) affects orthodontic tooth movement (OTM) through osteoclast inhibition. Furthermore, we analyzed the potential adverse effects of ATV on long-bone turnover and endochondral ossification.

Atorvastatin-induced osteoclast inhibition reduces orthodontic relapse.

Introduction: The statin class of drugs enhances osteogenesis and suppresses bone resorption, which could be a plausible biologic mechanism for mitigation of orthodontic relapse. We aimed to determine whether atorvastatin (ATV) might affect orthodontic relapse and osteoclastogenesis by modulating expression of RANKL and osteoprotegerin (OPG), crucial molecules involved in bone turnover. Furthermore, we analyzed the adverse effects of ATV on femur turnover and endochondral ossification.

Assessment of the dimensions and surface characteristics of orthodontic wires and bracket slots.

Objective: The purpose of this study was to evaluate the dimensions and surface characteristics of orthodontic wires and bracket slots of different commercial brands.

Methods: Thirty metallic brackets (0.022 x 0.

Feeding, artificial sucking habits, and malocclusions in 3-year-old girls in different regions of the world.

Purpose: The way babies and young children are reared is important to their health and development. Extensive breast-feeding has also been shown to reduce the development of artificial sucking habits like digit or pacifier-sucking. The aim of this study was to determine feeding methods, artificial sucking habits, and the presence of malocclusions in 3-year-old girls living in different regions of the world.

Bonded amalgam restorations: microleakage and tensile bond strength evaluation.

Purpose: The objective of this study was to evaluate the tensile bond strength (BS) and microleakage (MI) of bonded amalgam restorations to dentin when an unfilled and a filled system are used under three application modes.

Material And Methods: Seventy-two and 96 human molars, respectively, were employed for BS and MI tests. For BS, the occlusal surface of the molars was ground flat until dentin exposure.