Publications by authors named "Gabriel Paulraj Michael"

The present study was conducted to assess the mosquitocidal efficiency of compound isolated from Blumea mollis (D. Don) Merr against Culex quinquefasciatus. Eggs and larvae of Cx.

View Article and Find Full Text PDF

The present study was aimed to isolate active constituents from (Lam.) DC (Asteraceae) against phytopathogenic fungi. Bioactivity guided fractionation of the successive -hexane, chloroform and methanol extract led to the isolation of the monoterpene ester (4 ,5)-4-hydroxy-7-tigloyloxycarvotanacetone (1).

View Article and Find Full Text PDF

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that causes memory and cognitive deficits. The present study was carried out to evaluate the protective effects of fucoidan in monocrotophos induced AD in Drosophila melanogaster. In silico studies showed that fucoidan exhibited binding energy of -9.

View Article and Find Full Text PDF

A nanopesticide formulation was developed using chitosan and a botanical pesticide PONNEEM and its antifeedant, larvicidal and growth regulating activities were screened against Helicoverpa armigera, a major lepidopteran pest. Chitosan nanoparticles (CSNs) were prepared by using two different cross-linking agents namely glutaraldehyde (GLA) and tripolyphosphate (TPP). The effects of cross linking agents on CSNs and the biological properties against the insect pest were also studied.

View Article and Find Full Text PDF

The anticarcinogenic potential of the phytocompound Luteolin-7-O-Glucoside (LUT7G), isolated from the leaves of Ophiorrhiza mungos Linn, was studied against 4 different cancer cell lines (COLO 320 DM, AGS, MCF-7, and A549) and normal VERO cell line. The ability of LUT7G to induce apoptosis was determined by its antiradical activity, DNA fragmentation, expression of β-catenin, and chemopreventive efficacy in vivo by administering rats with DMH (20 mg/kg b.w.

View Article and Find Full Text PDF