The Effectiveness of Hyaluronic Acid in Controlling Pain, Edema, and Trismus After Extraction of Third Molars: Systematic Review and Meta-Analysis.

This study aimed to evaluate the clinical evidence of hyaluronic acid (HA) in minimizing inflammatory parameters such as pain, edema, and trismus after extraction of third molar (3M). An electronic search was conducted in 4 databases. The eligibility criteria included clinical trials that used HA compared with placebo or no treatment after 3M surgeries.