Publications by authors named "Gabriel Grubb"
Article Synopsis
- Doctors often check kidney function using two markers: creatinine and cystatin C.
- In 2010, using both markers together helped discover new kidney problems called selective glomerular hypofiltration syndromes, which are serious and can increase the risk of illness and death.
- The current guidelines don’t recommend cystatin C as a main marker, so many patients with these kidney issues might not be identified; experts believe cystatin C should be included in future guidelines.
Protein biomarkers have the potential to improve diagnosis, stratification of patients into treatment cohorts, follow disease progression and treatment response. One distinct group of potential biomarkers comprises proteins which have been linked to cancer, known as cancer associated proteins (CAPs). We determined the normal variation of 86 CAPs in 72 individual plasma samples collected from ten individuals using SRM mass spectrometry.
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