This study investigated the concentration of glyphosate in water (groundwater and surface), soil (top and sub) on cassava and maize farms within 3 farm settlements (Akufo, Ilora and Otiri Ipapo) from Ido, Oyo and Iseyin Local Government Areas of Oyo state, Nigeria. Samples of Top and sub soil were taken from the farms while water was collected from wells (groundwater) and streams (surface water) around each farm settlement using standard methods. Crops (cassava and Maize) samples were collected from each of the selected farm after harvest.
View Article and Find Full Text PDFToxicol Rep
June 2023
Background: Cannabis and cannabinoids affect almost every system of the body and exert systemic effects such as alterations in memory and cognitive functions, neurotransmission impediment, as well as obstruction of endocrine and reproductive system functions. Reproduction is a complicated phenomenon that integrates biological, psychological and behavioural aspects, hence susceptible to intracellular and extracellular modulations by numerous chemicals and toxicants like cannabis.
Aim: The effects of early-life exposure to cannabis on reproductive function biomarkers and genes were investigated in male and female Wistar rats in this study.
There is an increasing overdependence and use of atrazine herbicide for the control of pre-and post-emergence broad leaf weeds on maize farms in rural agricultural communities in Nigeria. We carried out a survey of atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH) and 4 streams from all the 6 communities (Awa, Mamu, Ijebu-Igbo, Ago-Iwoye, Oru and Ilaporu) in Ijebu North Local Government Area, Southwest Nigeria. The effect of the highest concentration of atrazine detected in the water from each of the communities on the hypothalamic-pituitary-adrenal (HPA) axis of albino rats was investigated.
View Article and Find Full Text PDFNo recognized study has been conducted in rural agricultural areas in Nigeria to monitor atrazine in drinking water and its potential health implications. Here, a total of 69 hand-dug wells (HDW), 40 boreholes (BH), and 4 streams were collected from the six (6) communities in Ijebu-North Local Government Area, Southwest Nigeria and analyzed for atrazine residue using gas chromatography-mass spectrometry (GC-MS). Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal routes in children and adults using the standard US EPA protocols.
View Article and Find Full Text PDFNo recognised study has been conducted to monitor atrazine residue in drinking water from rural agricultural areas in Nigeria and its potential health implications. In this ecotoxicological study, we monitored atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH) and 4 major streams from all the 6 communities (Ago-Iwoye, Ijebu-Igbo, Oru, Awa, Ilaporu and Mamu) in Ijebu North Local Government Area, Southwest Nigeria. Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal contact in adults and children as well as neurotoxicity assessment.
View Article and Find Full Text PDFThere are no available data on the level of atrazine in drinking water from rural agricultural areas in Nigeria and its potential health implications. Here, we measured atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH), and four major streams from the six communities (Ago-Iwoye, Ijebu-Igbo, Oru, Awa, Ilaporu, and Mamu) in Ijebu North Local Government Area, Southwest Nigeria. Values of atrazine obtained were further used for the evaluation of non-carcinogenic risk associated with ingestion and dermal contact in adults and children as well as reproductive toxicity evaluation.
View Article and Find Full Text PDFSci Rep
February 2022
Soil transmitted helminth (STH) infections are among the most common human infections worldwide with over 1 billion people affected. Many estimates of STH infection are often based on school-aged children (SAC). This study produced predictive risk-maps of STH on a more finite scale, estimated the number of people infected, and the amount of drug required for preventive chemotherapy (PC) in Ogun state, Nigeria.
View Article and Find Full Text PDFWhile the impact of glyphosate-based herbicides (GBHs) on earthworms has been studied, little is known about their effects on the earthworm gut microbiome. This study investigated the impact of a GBH on the gut microbial communities of three earthworm species ( and ). Earthworm species accommodated in soil were sprayed with 115.
View Article and Find Full Text PDFBackground: In addition to improving soil fertility and crop production, earthworms have been found to be useful in the removal of contaminants from soil, known as vermiremediation. Previous studies on vermiremediation have focused primarily on organic wastes, with relatively less attention paid to inorganic contaminants. In addition, some basic terms used in environmental health studies have often not been properly clarified.
View Article and Find Full Text PDFOil exploration's devastation on health and the environment may far outweigh its economic benefits. An oil spill occurred at Egbokodo River in Delta State, Nigeria, thereby polluting the land and water bodies. The study was therefore aimed at evaluating the impacts of iron, lead, cadmium, and chromium on the zooplankton community structure of Egbokodo River and the potential health risks.
View Article and Find Full Text PDFIn most endemic sub-Saharan African countries, repeated infections with soil-transmitted helminth (STH) occur as early as six weeks after the end of mass drug administration (MDA) with albendazole. In this study, we designed a new health educational board game Worms and Ladders and evaluated its potential to complement MDA with albendazole and reduce reinfection rates through the promotion of good hygiene practices among school-aged children. The evaluation employed a randomized control trial (RCT) design.
View Article and Find Full Text PDFBackground: Ascariasis, Trichuriasis and Hookworm infections poses a considerable public health burden in Sub-Saharan Africa, and a sound understanding of their spatial distribution facilitates to better target control interventions. This study, therefore, assessed the prevalence of the trio, and mapped their spatial distribution in the 20 administrative regions of Ogun State, Nigeria.
Methods: Parasitological surveys were carried out in 1,499 households across 33 spatially selected communities.
The aim of the study was to comparatively analyze the interrelationships among iron (Fe), manganese (Mn), zinc (Zn), copper (Cu), lead (Pb), cadmium (Cd), chromium (Cr) and total hydrocarbons (THCs) in the gills, intestines and muscles of Clarias gariepinus collected from Osse River, Nigeria, between the periods of April, 2013 to September, 2014. The trace metals in the fish tissues were analyzed using Atomic Absorption Spectrophotometer (AAS, Philips model PU 9100), while total hydrocarbons were analyzed using High Performance Liquid Chromatograph (HPLC,Prominence Dual brand from HGE) equipped with a detector Shimadzu UV-Visible (UV-Vis Prominence SPD 20 A). The concentrations of trace metals and THCs in the tissues were subjected to principal component analysis (PCA), in conjunction with hierarchical cluster analysis (HCA), backed up by correlation analysis (CA).
View Article and Find Full Text PDFIt remains unknown if casts produced by earthworms exposed to a glyphosate-based herbicide (GBH) will retain their agricultural benefit. This study investigated the agricultural importance of surface casts produced by three earthworm species (Alma millsoni, Eudrilus eugeniae and Libyodrilus violaceus) exposed to a GBH on growth, fruit yield and quality of tomato (Lycopersicon esculentum). We sprayed 60 buckets (i.
View Article and Find Full Text PDFThere have been growing concerns and uncertainty about reports attributing the metabolic disturbance induced by a commercial formulation of glyphosate-based herbicide to its active ingredient. We therefore compared the effects of Roundup Original® and its active ingredient glyphosate on some hypothalamic-pituitary-adrenal (HPA) hormones and oxidative stress markers, biochemical and hematological profiles in 56 adult male albino rats randomly assigned to seven treatments of eight rats per treatment. The rats were orally exposed to Roundup Original® and its active ingredient daily at 3.
View Article and Find Full Text PDFThere have been major concerns that the nephrotoxicity of commercial formulations of Roundup herbicide is due to the active ingredient glyphosate. We therefore investigated and compared the mechanisms underlining the nephrotoxicity of Roundup herbicide and glyphosate alone in rat. Fifty-six adult male rats randomized into 7 groups of 8 rats per group were exposed to Roundup formulation and glyphosate alone daily by gavage at 3.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
February 2018
The increase in the frequency of exposure to gasoline fumes and the growing incidence of infertility among humans has been a major concern and subject of discussion over the years in Nigeria. We therefore present the reproductive effect of gasoline fumes on inhalation exposure in 40 male albino rats. The rats were randomized into five experimental treatments (T) with eight rats per treatment.
View Article and Find Full Text PDFThe incidence of infertility in human is on the increase and the use of Roundup herbicide and presence of its residues in foodstuff is a major concern. This study therefore aim to assess the effect of Roundup on the reproductive capacity of 32 adult male albino rats randomized into 4 groups of 8 rats per group orally exposed to Roundup at 3.6mg/kg body weight(bw), 50.
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