Publications by authors named "Gabriel Ademola Olatunji"

Article Synopsis
  • * Researchers developed new compounds, DHA-PABA and DHA-LEVO, and confirmed their structures using advanced techniques like FT-IR and NMR, then tested their effectiveness as antimalarials in mice.
  • * The new pyrano-benzodioxepin derivatives showed potential as fast-acting treatments, effectively reducing parasite levels in the blood and suggesting further development for tackling resistant malaria strains.
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The undesirable environmental impacts of inappropriate application of pesticides have brought about research into new matrices for controlled release of pesticides. Porous starch citrate biopolymer was designed for the release of carbofuran in this experiment and characterized using Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Thermo-Gravimetric Analysis (TGA) for functional group, surface morphology and thermal stability properties respectively. The SEM revealed highly stabilized porous starch citrate biopolymers with porous structures and gradients suitable for controlled release studies.

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A new steroidal ester bearing -nonadecanoyl moiety () and a mixture of isomeric cerebrosides () along with two known compounds were isolated from the methanol extract of the stem-bark of . The structure of the new steroidal ester was determined as 3--nonadecanoyl-β-sitosterol on the basis of modern spectroscopic techniques (IR, ESI-MS, HR-ESIMS, 1D and 2D NMR) and chemical degradation studies. The structures of the known compounds were identified as gallic acid and tanacetene by comparison of the spectroscopic data with those of reported data.

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A bioassay-guided fractionation of an alcoholic extract from the peels of Ipomoea batatas Lam has been carried out. Sulforhodamine B and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays were used to evaluate the anticancer and antioxidant potential, respectively, while silica gel column chromatography (CC) was used to isolate compounds that were characterized using 1D- and 2D-NMR (Nuclear Magnetic Resonance) and mass spectrometry. The alcoholic extract was fractionated into n-hexane, ethyl acetate, n-butanol, and water.

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