Spectrochim Acta A Mol Biomol Spectrosc
October 2021
Photodynamic Therapy (PDT) is a powerful technique for the treatment of cancer and non-cancerous diseases. The precise PDT treatment protocol definition must consider the performance difference between in vitroand in vivoapplications. This also occurs in other biological studies, and to partially overcome this difficulty, the simulated body fluids are generally applied as a prior understanding of the particularities of the different systems.
View Article and Find Full Text PDFThe mode-mismatched dual-beam thermal lens technique is widely applied in the characterization of optical and thermo-physical properties of solids and liquids. The technique has also been used to investigate transient acoustic waves induced by pulsed laser excitation at the nanosecond time scale. In this paper, we developed a semi-analytical model to describe the transient acoustic wave that allows a fitting procedure to get the physical properties of fluid samples.
View Article and Find Full Text PDFWe use the thermal lens technique in the nanosecond time scale to describe the acoustic wave effect in liquids and the corresponding correlation with the speed of sound in the fluid, volumetric thermal expansion, and piezo-optic coefficient. These physical properties are found to be directly correlated to the anomalous effects observed in the transients at the nanosecond time scale, where acoustic waves dominate the thermal lens signal inducing an oscillating transient. Our results suggest the application of the thermal lens to study the generation and the detection of thermo-acoustic waves in liquids, which makes this method interesting for all-optoacoustic ultrasound detection and imaging.
View Article and Find Full Text PDF