Publications by authors named "Gabor Szakacs"
Magnesium alloys are promising candidates for biodegradable medical implants which reduce the necessity of second surgery to remove the implants. Yttrium in solid solution is an attractive alloying element because it improves mechanical properties and exhibits suitable corrosion properties. Silver was shown to have an antibacterial effect and can also enhance the mechanical properties of magnesium alloys.
View Article and Find Full Text PDFArticle Synopsis
- The study examined how biodegradable magnesium (Mg) and its alloys (Mg2Ag and Mg10Gd) affect the growth and properties of MC3T3-E1 cells when they come into contact with the materials.
- It was found that surface changes due to corrosion, especially crystal formation on Pure Mg and Mg2Ag after 8 days, negatively impact cell viability, while non-corroded surfaces allow for better cell survival.
- Notably, Mg10Gd showed improved expression of collagen I and Runx2 markers for cell differentiation after 8 to 12 days, suggesting its potential benefits for orthopedic applications by enhancing osteointegration.
In vitro and in vivo comparison of binary Mg alloys and pure Mg.
Mater Sci Eng C Mater Biol Appl
April 2016
Biodegradable materials are under investigation due to their promising properties for biomedical applications as implant material. In the present study, two binary magnesium (Mg) alloys (Mg2Ag and Mg10Gd) and pure Mg (99.99%) were used in order to compare the degradation performance of the materials in in vitro to in vivo conditions.
View Article and Find Full Text PDF