[The complex dental and oral surgical management with 8-year follow up of a Gorlin‒Goltz syndrome patient].

Gorlin-Goltz syndrome is an autosomal dominant hereditary disease. Its leading symptoms include keratocysts of the jaws, multiple basal cell carcinomas, skeletal abnormalities, intracranial calcifications and dyskeratosis of the soles and palms. One of the most common and often firstly discovered symptoms is the single or multiplex keratocysts of the jaws.

[Study of salivary biomarkers for oral squamous cell carcinoma in patients with type-2 diabetes].

According to the latest epidemiological data the occurrence of oral squamous cell carcinoma has increased recently in the last 4 decades. In spite of the great emphasis and effort in the field of prevention, novel medication therapy, our knowledge has to be enlarged in the development of this serious disease. Recent epidemiological studies and animal experiments have shown that there is a relationship between type-2 diabetes and oral squamous cell carcinoma.

Salivary proteomic analysis of diabetic patients for possible oral squamous cell carcinoma biomarkers.

Since oral squamous cell carcinoma (OSCC) is one of the most important causes of death worldwide, the prevention and early detection plays a crucial role. Recent epidemiological studies have incriminated diabetes as a risk factor for the development of OSCC, as well as oral premalignant lesions. As for the last 20 years diabetes and oral squamous cell carcinoma rates have been increasing rapidly, therefore a reliable detection method of major saliva proteins as possible biomarkers for OSCC is of key priority.

Application of platysma-based transpositional flap for through-and-through facial defect when the facial artery circulation is blocked or compromised.

Purpose: A novel use of site-limited platysma-based transpositional flap is demonstrated and discussed for the reconstruction of facial defects.

Materials And Methods: Between January 1985 and January 2001, 342 patients were operated on for advanced oral-oropharyngeal and orofacial cancers. In 6 cases, a platysma-based transpositional flap was used for external closure of facial through-and-through defects.