Automatic Compliance Checking (ACC) within the Architecture, Engineering, and Construction (AEC) sector necessitates automating the interpretation of building regulations to achieve its full potential. Converting textual rules into machine-readable formats is challenging due to the complexities of natural language and the scarcity of resources for advanced Machine Learning (ML). Addressing these challenges, we introduce CODE-ACCORD, a dataset of 862 sentences from the building regulations of England and Finland.
View Article and Find Full Text PDFObesity is a modifiable risk factor for breast cancer. Yet, how obesity contributes to cancer initiation is not fully understood. The goal of this study was to determine if the body mass index (BMI) and metabolic hallmarks of obesity are related to DNA damage in normal breast tissue.
View Article and Find Full Text PDFMethanolic extract from was investigated for its phytochemical content, antioxidant, and antimicrobial properties against phytopathogenic fungi and bacteria. Phytochemical analysis revealed the presence of saponin, tannins, and alkaloids with 1.25%, 18.
View Article and Find Full Text PDFThe current work reports the synthesis of Cr(iii), Mn(ii), Co(ii), Ni(ii) and Cu(ii) chelates of the Schiff base ligand named hydroxy-phenyl-acetic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide with multi-chelation centre toward metal ions. The spectral tools, H-NMR, FTIR, mass, UV-vis spectra, and the analytical elemental and thermal analysis, in addition to magnetic moment and conductivity measurements all combined have been applied to conclude the structure and geometry of the synthesized metal complexes. The formed metal chelates have been assured to be formed with the molar compositions of 1 L : 1 M for PANH-Cr, PANH-Mn, PANH-Co, PANH-Ni and 2 L : 1 M for PANH-Cu.
View Article and Find Full Text PDFTrifluoromethyl arenes (Ar-CF) are amongst the commonly encountered fluorinated substructures in pharmaceutical, agrochemical, and material sciences. However, predominant methods to access Ar-CF possess several limitations, including harsh conditions, lack of availability of substrates, and poor regioselectivity, which combined restrict access to desirable highly functionalized Ar-CF-containing compounds. To expand the scope of accessible Ar-CF-based molecules, we present an orthogonal deoxyfluoroalkylation/aromatization approach that exploits readily accessible and programable cyclohexan(en)one substrates, which undergo a reliable 1,2-addition reaction with the Ruppert-Prakash reagent (TMSCF) followed by aromatization to deliver highly functionalized Ar-CF compounds in a one/two-pot sequence.
View Article and Find Full Text PDFThis study presents novel composites of biochar (BC) derived from spinach stalks and zinc oxide (ZnO) synthesized from water hyacinth to be used for the first time in a hybrid system for activating persulfate (PS) with photocatalysis for the degradation of bromothymol blue (BTB) dye. The BC/ZnO composites were characterized using innovative techniques. BC/ZnO (2:1) showed the highest photocatalytic performance and BC/ZnO (2:1)@(PS + light) system attained BTB degradation efficiency of 89.
View Article and Find Full Text PDFUnlabelled: The intersectional risks of children in United States immigrant communities include environmental exposures. Pesticide exposures and their biological outcomes are not well characterized in this population group. We assessed pesticide exposure and related these exposures to DNA double-strand breaks (DSBs) in Latinx children from rural, farmworker families (FW; = 30) and from urban, non-farmworker families (NFW; = 15) living in North Carolina.
View Article and Find Full Text PDFThe prevalence of Metabolic-associated fatty liver disease (MAFLD) has been steadily increasing worldwide, paralleling the global epidemic of obesity and diabetes. It is estimated that approximately one-quarter of the global population is affected by MAFLD. Despite its high prevalence, MAFLD often goes undiagnosed due to the lack of specific symptoms in its early stages.
View Article and Find Full Text PDFIn recent years, major advances in our understanding of risk factors implicated in the development of cardiovascular disease (CVD), in available tools for early detection of CVD, and in effective interventions to prevent subclinical or clinically manifest disease, have led to an increasing appreciation of prevention as a major pillar of cardiovascular (CV) medicine. Preventive Cardiology has evolved into a dynamic sub-speciality focused on the promotion of CV health through all stages of life, and on the management of individuals at risk of developing CVD or experiencing recurrent CV events, through interdisciplinary care in different settings. As the level of knowledge, specialized skills, experience, and committed attitudes related to CV prevention has exceeded core cardiology training, the European Association of Preventive Cardiology (EAPC) has placed major emphasis on continuous education and training of physicians and allied professionals involved in CV prevention, with the aim of setting standards for practice and improving quality of care.
View Article and Find Full Text PDFAnti-Spike IgG antibodies against SARS-CoV-2, which are elicited by vaccination and infection, are correlates of protection against infection with pre-Omicron variants. Whether this association can be generalized to infections with Omicron variants is unclear. We conducted a retrospective cohort study with 8457 blood donors in Tyrol, Austria, analyzing 15,340 anti-Spike IgG antibody measurements from March 2021 to December 2022 assessed by Abbott SARS-CoV-2 IgG II chemiluminescent microparticle immunoassay.
View Article and Find Full Text PDFThis study utilized to produce selenium nanoparticles (Se-NPs) in an environmentally friendly and ecologically sustainable manner, targeting several medicinal applications. These biosynthesized Se-NPs were meticulously characterized using X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, transmission electron microscope (TEM), and UV-visible spectroscopy (UV), revealing their spherical shape and size ranging between 28 and 78 nm. We conducted further testing of Se-NPs to evaluate their potential for biological applications, including antiviral, anticancer, antibacterial, antioxidant, and antibiofilm activities.
View Article and Find Full Text PDFA new modified cellulose with diaminoguanidine (Cel-Gua) synthesized for specific recovery of Cu (II), Cd (II), and Hg (II) from the alum sample. Cellulose was silanized by 3-chloropropyltrimethoxysilane and then was modified with diaminoguanidine to obtain N-donor chelating fibers. Fourier transform-infrared spectroscopy, scanning electron microscopy, X-ray diffraction, zeta potential, electrons disperse X-ray analysis, elemental analyses (C, H and N), and thermogravimetric analysis were used for characterization.
View Article and Find Full Text PDFA twelve week feeding experiment was conducted to evaluate the replacement of fishmeal (FM) with poultry by-product meal (PBM) in practical diets for European sea bass, with an average initial weight of 0.89 g. Five isocaloric (5.
View Article and Find Full Text PDFSolidification/Stabilization (S/S) of spent radioactive ion exchange resins (IER) is one of many critical problems facing developing nuclear industries all over the world. Immobilization technology using Ordinary Portland Cement (OPC) as an inert matrix, has been widely applied for the solidification/stabilization of spent ion exchange resin. In this study incorporation of simulated IER into cement matrix and characterization of the final solid waste form (FWF) had been searched practically in laboratory scale experiments.
View Article and Find Full Text PDFElectro-regeneration is emerging as a new technique to regenerate spent carbon adsorbents through an electrochemical process. In this study, sequential adsorption and electro-regeneration of ciprofloxacin (CIP)-laden carbon were investigated using both pristine and iron (Fe)-doped F400 activated carbon in distilled, deionized (DI) water and reverse osmosis (RO) concentrate water. The impact of reactor flow rate and sequential adsorption/electro-regeneration cycles on the regeneration efficiency were also evaluated.
View Article and Find Full Text PDFBackground: To provide updated estimates on SARS-CoV-2 antibody seroprevalence and average antibody titres for Central Europe.
Methods: In repeat cross-sectional investigations (1 May 2022 to 9 March 2023) involving 28,768 blood donors in the Federal State of Tyrol, Austria (participation rate: 87.0%), we measured Spike receptor-binding domain (RBD) and Nucleocapsid IgG antibodies (37,065 and 12,645 samples), and estimated monthly seroprevalences and geometric mean titres.
: Urinary tract infections [UTIs] are considered the third most known risk of infection in human health around the world. There is increasing appreciation for the pathogenicity of Gram-positive and Gram-negative strains in UTIs, aside from fungal infection, as they have numerous virulence factors. : In this study, fifty urine samples were collected from patients suffering from UTI.
View Article and Find Full Text PDFA novel biochar (BC), derived from spinach leaves, was utilized as an activator for persulfate (PS) in the degradation of methylene blue (MB) dye under visible light conditions. Thorough analyses were conducted to characterize the physical and chemical properties of the biochar. The (BC + light)/PS system exhibited superior MB degradation efficiency at 83.
View Article and Find Full Text PDFIn this study, novel nanohybrids of biosynthesized zinc oxide (ZnO) and magnetite-nanocarbon (FeO-NC) obtained from the carbonization of toner powder waste were fabricated and investigated for persulfate (PS) activation for the efficient degradation of tetracycline (TCN). The chemical and physical properties of the synthesized catalysts were analyzed using advanced techniques. ZnO/FeO-NC nanohybrid with mass ratio 1:2, respectively in the presence of PS showed the highest TCN removal efficiency compared to the individual components (ZnO and FeO-NC) and other nanohybrids with mass ratios of 1:1 and 2:1.
View Article and Find Full Text PDFBackground: Proprotein convertase subtilisin/kexin type 9 (PCSK-9) is a circulating protein that plays an important role in lipid metabolism and is linked to inflammation, which has implications for atherosclerosis and its severe cardiac effects. We studied the potential association of the PCSK-9 gene single nucleotide polymorphism (SNP), Oxidized low-density lipoprotein receptor 1- (OLR-1), and caspase-3 serum levels with the risk and severity of premature coronary artery disease (PCAD). The potential contribution of PCSK-9 serum level to the severity of PCAD patients was also assessed.
View Article and Find Full Text PDFBackground & Objectives: Objective assessment of post-COVID-19 cognitive dysfunction is highly warranted. This study aimed to evaluate the cognitive dysfunction of COVID-19 survivors with cognitive complaints, both clinically and neurophysiologically, using Quantitative Electroencephalogram (QEEG).
Methods: This case-control study was conducted on 50 recovered subjects from COVID-19 infection with cognitive complaints and 50 age, sex, and educational-matched healthy controls.
In this work, a novel isatin-Schiff base L2 had been synthesized through a simple reaction between isatin and 2-amino-5-methylthio-1,3,4-thiadiazole. The produced Schiff base L2 was then subjected to a hydrothermal reaction with cerium chloride to produce the cerium (III)-Schiff base complex C2. Several spectroscopic methods, including mass spectra, FT-IR, elemental analysis, UV-vis, C-NMR, H-NMR, Thermogravimetric Analysis, HR-TEM, and FE-SEM/EDX, were used to completely characterize the produced L2 and C2.
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