Nanoparticle-Embedded Polymers and Their Applications: A Review.

There has been increasing interest in the study and development of nanoparticle-embedded polymeric materials and their applications to special membranes. Nanoparticle-embedded polymeric materials have been observed to have a desirable compatibility with commonly used membrane matrices, a wide range of functionalities, and tunable physicochemical properties. The development of nanoparticle-embedded polymeric materials has shown great potential to overcome the longstanding challenges faced by the membrane separation industry.

Preparation of Cu/Sn-Organic Nano-Composite Catalysts for Potential Use in Hydrogen Evolution Reaction and Electrochemical Characterization.

In this work, the solvothermal solidification method has been used to be prepared as a homogenous CuSn-organic nano-composite (CuSn-OC) to use as a catalyst for alkaline water electrolysis for cost-effective H generation. FT-IR, XRD, and SEM techniques were used to characterize the CuSn-OC which confirmed the formation of CuSn-OC with a terephthalic acid linker as well as Cu-OC and Sn-OC. The electrochemical investigation of CuSn-OC onto a glassy carbon electrode (GCE) was evaluated using the cyclic voltammetry (CV) method in 0.

Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition.

Novel semisynthetic coumarin derivatives were synthesized to be developed as chemotherapeutic anticancer agents through topoisomerase II, VEGFR2 inhibition that leads to apoptotic cancer cell death. The coumarin amino acids and dipeptides derivatives were prepared by the reaction of coumarin-3-carboxylic acid with amino acid methyl esters following the ,-dicyclohexylcarbodiimide (DCC) method and 1-hydroxy-benzotriazole (HOBt), as coupling reagents. The synthesized compounds were screened towards VEGFR2, and topoisomerase IIα proteins to highlight their binding affinities and virtual mechanism of binding.

Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent.

A convenient protocol was developed for the transformation of -aryl-substituted benzamides to -aryl-substituted benzothioamides using -isopropyldithiocarbamate isopropyl ammonium salt as a novel thiating reagent. The major advantages of this protocol are its procedure, short reaction times, mild conditions, simple work-up, high yields and pure products.

Convenient Synthesis of -Alkyl-2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetamides and Methyl-2-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetylamino]alkanoates.

A series of 27 new quinoxaline derivatives (-alkyl-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)]acetamides, methyl-2-[2-(3-phenylquinoxalin-2-ylsulfanyl)-acetylamino]alkanoates, and their corresponding dipeptides) were prepared from 3-phenylquinoxaline-2(1)-thione based on the chemoselective reaction with soft electrophiles. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to study the efficacy of 27 compounds on cancer cell viability and proliferation. A total of 13 compounds (-, , , , , , , , , , and ) showed inhibitory action on HCT-116 cancer cells and 15 compounds (-, , , , , , , , , , , , and ) showed activity on MCF-7 cancer cells, with compound exhibiting the highest inhibitory action (IC 1.

Synthesis of Novel Phthalazinedione-Based Derivatives with Promising Cytotoxic, Anti-bacterial, and Molecular Docking Studies as VEGFR2 Inhibitors.

The parent ester methyl-3-[2-(4-oxo-3-phenyl-3,4-dihydro-phthalazin-1-yloxy)-acetylamino] has 18 compounds. The starting material for alkanoates, their corresponding hydrazides, hydrazones, and dipeptides were produced by chemoselective O-alkylation of 2-phenyl-2,3-dihydrophthalazine-1,4-dione with ethyl chloroacetate(4-oxo-3-phenyl-3,4-dihydro-phthalazin-1-yloxy) acetic acid methyl ester. The starting ester was hydrazinolyzed, then azide coupled with amino acid ester hydrochloride to produce several parent esters, and then hydrazinolyzed to produce parent hydrazides.

Sonochemical assisted fabrication of 3D hierarchical porous carbon for high-performance symmetric supercapacitor.

A scalable fabrication of 3D hierarchical porous carbon structure (3D-HPC) has been achieved via a simple sonochemical route at different pyrolysis temperatures. It is worth noting that all the 3D-HPC samples possess oxygen-functional groups after activation by KOH and self-doped by nitrogen, which are beneficial to improving their surface wettability as well as increasing the electro-active surface area between the electrode and the surrounding electrolyte, consequently enhancing their electrochemical performance. Remarkably, the resulting carbon sample pyrolyzed at 850 °C (AC-850) possesses a maximum doping level of 2.

Spectroscopic analyses of iron doped protonated polyaniline/graphene oxide system.

Fe and H co-doped PANI/GO (graphene oxide) composites with different iron dopant ratio depending on the starting FeCl (GOPNI-1, GOPNI-2, GOPNI-3 and GOPNI-4) are prepared. The formations of composite samples are investigated by some characterization techniques such as XRD, ATR-IR, UV-Vis spectrophotometer and thermal properties by TGA. While, the Nitrogen adsorption/desorption isotherm for (GOPNI-3) shows high specific surface area 48.