New insights and investigation: Morphomolecular notes on the infraciliature, taxonomy, and systematics of pleurostomatid ciliates (Protozoa, Ciliophora), with establishment of a new suborder, two new genera, and three new species.

Pleurostomatid ciliates, as a highly diverse and widely distributed unicellular eukaryote group, play a crucial role in the cycling of nutrients and energy in microbial food webs. However, research on pleurostomatids remains insufficient, resulting in a paucity of molecular information and substantial gaps in knowledge of their phylogenetic relationships. In recent years, we investigated pleurostomatid diversity in various Chinese habitats, including their systematic relationships and taxonomic circumscriptions, which were comprehensively analyzed using an integrative morphomolecular approach.

Modeling feedback processes between soil detachment and sediment transport along hillslopes on the Loess Plateau of China.

A dynamic model of soil erosion along hillslopes considering soil detachment and sediment transport is still a major challenge in terms of its applicability to field conditions. Data availability for model calibration and validation is very limited for physically process models. An improved hillslope erosion dynamic model (HED) with a simple structure and strong application on field plots was established based on the sediment feedback mechanism in this study.

Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium.

Repurposing existing drugs to inhibit SARS-CoV-2 infection in airway epithelial cells (AECs) is a quick way to find novel treatments for COVID-19. Computational screening has found dicoumarol (DCM), a natural anticoagulant, to be a potential SARS-CoV-2 inhibitor, but its inhibitory effects and possible working mechanisms remain unknown. Using air-liquid interface culture of primary human AECs, we demonstrated that DCM has potent antiviral activity against the infection of multiple Omicron variants (including BA.

Protection of laryngeal mucosa and function in laryngeal burns by heat absorption of perilaryngeal tissue.

Objective: The laryngeal tissue carries most of the heat during inhalation injury. This study aims to explore the heat transfer process and the severity of injury inside laryngeal tissue by horizontally studying the temperature rise process at various anatomical layers of the larynx and observing the thermal damage in various parts of the upper respiratory tract.

Methods: The 12 healthy adult beagles were randomly divided into four groups, and inhaled room temperature air (control group), dry hot air of 80 °C (group I), 160 °C (group II), and 320 °C (group III) for 20 min, respectively.

Chitosan derivatives as promising green corrosion inhibitors for carbon steel in acidic environment: Inhibition performance and interfacial adsorption mechanism.

Among the biodegradable polysaccharide, chitosan is widely present in the cell membranes of bacteria and algae and in the cell walls of higher plants. As a promising biopolymer, chitosan has great potential as eco-friendly corrosion inhibitor. Herein, two synthetic chitosan derivatives (N-phenylthiourea chitosan (CS-PT), N-phenyl-O-benzylthiourea chitosan (CS-PT-Bn)) were investigated as high-efficient acidic corrosion inhibitors to deal with the corrosion issue of carbon steel.

In-depth unveiling the interfacial adsorption mechanism of triazine derivatives as corrosion inhibitors for carbon steel in carbon dioxide saturated oilfield produced water.

In this work, two triazine derivatives (BTT-1 and BTT-2) were synthesized by the simple one-step condensation of three components and used as high-efficient corrosion inhibitors to deal with the corrosion issue of carbon steel (CS) in petroleum industry. Electrochemical tests indicate that both BTT-1 and BTT-2 present superior inhibition performance with the inhibition efficiency of 97.9 % and 98.

Epidemiology and risk prediction of patients with severe burns admitted to a burn intensive care unit in a burn center in beijing: A 5-year retrospective study.

Objective: This study was performed to describe the epidemiology of patients with severe burns hospitalized in a burn intensive care unit (BICU), explore the risk factors associated with the patients' outcomes and evaluate the ability of prognostic scoring systems as risk prediction of mortality.

Methods: The data for this study were derived from patients with severe burns in the BICU of Beijing Jishuitan Hospital from 2015 to 2019. The following epidemiological information and outcomes were collected for retrospective analysis: sex, age, date of injury, etiology of burn, admission time after injury, extent of burn, inhalation injury, length of stay, and outcome.

Role of tribochemistry reactions of BC on tribofilm growth at a PEEK-steel interface in simulated body fluids.

Corrosion and wear products of metallic implants can lead to severe adverse tissue reactions. However, there is an absence of effective means to reduce the tribocorrosion of metal. The main purpose of this study is to reveal a mechanism of engineering a barrier layer on metal surfaces adding functional particles into the polymer counterpart.

[Systematic review of the epidemiological characteristics of inhalation injury in burn patients in China].

To study the epidemiological characteristics of inhalation injury in burn patients in China. The systematic review method was performed. -, and were searched with the Chinese search terms of ", , ", and and were searched with the search terms of "burns, inhalation injury" to retrieve the collected retrospective studies on the epidemiological characteristics of inhalation injury in burn patients in China from the establishment of each database to January 2019.

The nucleolus functions as the compartment for histone H2B protein degradation.

Histones are main components of chromatin, and the protein levels of histones significantly affect chromatin assembly. However, how histone protein levels are regulated, especially whether and how histones are degraded, is largely unclear. Here, we found that histone H2B is mainly degraded through the proteasome-mediated pathway, and the lysine-120 site of H2B is essential for its K48-linked polyubiquitination and degradation.

Effective corrosion inhibition of mild steel by eco-friendly thiourea functionalized glucosamine derivatives in acidic solution.

In the view of environmental protection and sustainable development, the application of green effective inhibitors for metal corrosion in industry field is of great significance. In this work, two thiourea functionalized glucosamine derivatives, 5-hydroxy-1-phenyl-4-(1,2,3,4-tetrahydroxybutyl)imidazolidine-2-thione (GA-1) and 1-phenyl-3-(2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)thiourea (GA-2), were synthesized as eco-friendly corrosion inhibitors for mild steel (MS) in 1 M HCl solution, and their inhibition performance were evaluated by electrochemical tests and surface analyses. The electrochemical tests and surface analyses indicate that both GA-1 and GA-2 have high inhibition performance.

Inhibitive and adsorption behavior of thiadiazole derivatives on carbon steel corrosion in CO-saturated oilfield produced water: Effect of substituent group on efficiency.

Three thiadiazole derivatives with different substituent groups, 2-(benzylthio)-5-methyl-1,3,4-thiadiazole(BMT), 2-(benzylthio)-5-(butylthio)-1,3,4-thiadiazole(BBT), and 5-(benzylthio)-1,3,4-thiadiazole-2-thiol(BTT), were synthesized and studied as the corrosion inhibitors for N80 carbon steel in CO-saturated oilfield produced water. It is found that the synthesized thiadiazole derivatives could effectively inhibit the corrosion of N80 carbon steel by chemisorption. The corrosion inhibition performance of the organic compounds is in the order: BTT > BBT > BMT.

Impact of Elevated Body Mass Index on Surgical Outcomes for Patients Undergoing Cervical Fusion Procedures: A Systematic Review and Meta-Analysis.

To investigate whether high body mass index (BMI) had adverse effects on the postoperative outcomes for patients who underwent anterior or posterior cervical fusion procedures. A literature search were conducted in PubMed, Embase, and Web of Science. Comparative or controlled studies that examined the influences of high BMI on postoperative outcomes after cervical fusion procedures were included.

Efficacy of Vertebroplasty in Short-Segment Pedicle Screw Fixation of Thoracolumbar Fractures: A Meta-Analysis.

BACKGROUND Short-segment pedicle screw instrumentation provides superior outcomes in treating thoracolumbar fractures. Nevertheless, the effect of intermediate screws on the outcome of short-segment instrumentation at the fracture level has not been specifically analyzed. We performed an update meta-analysis of the effect of additional vertebroplasty on the outcome of short-segment instrumentation to determine the role of screws for patients with fractured vertebra.

An updated meta-analysis of clinical outcomes comparing minimally invasive with open transforaminal lumbar interbody fusion in patients with degenerative lumbar diseases.

Background & Aims: Open-transforaminal lumbar interbody fusion (O-TLIF) is regarded as the standard (S) approach which is currently available for patients with degenerative lumbar diseases patients. In addition, minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) has proposed and gradually obtained popularity compared with O-TLIF procedures due to its beneficial outcomes in minimized tissue injury and quicker recovery. Nonetheless, debates exist concerning the use of MI-TLIF with its conflicting outcomes of clinical effect and safety in several publications.

Late deep cervical infection after anterior cervical discectomy and fusion: a case report and literature review.

Background: Anterior cervical discectomy and fusion (ACDF) is often performed for the treatment of degenerative cervical spine. While this procedure is highly successful, 0.1-1.

Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53.

Monoubiquitination of histone H2B on lysine 120 (H2Bub1) is an epigenetic mark generally associated with transcriptional activation, yet the global functions of H2Bub1 remain poorly understood. Ferroptosis is a form of non-apoptotic cell death characterized by the iron-dependent overproduction of lipid hydroperoxides, which can be inhibited by the antioxidant activity of the solute carrier family member 11 (SLC7A11/xCT), a component of the cystine/glutamate antiporter. Whether nuclear events participate in the regulation of ferroptosis is largely unknown.

Unilateral versus bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures in elderly patients: A meta-analysis.

Objective: To contrast the effects and complications in unilateral and bilateral percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures in elderly patients.

Methods: Multiple databases were adopted to search relevant studies, and the articles eventually satisfied the criteria were included. All the meta-analyses were conducted with the Review Manager 5.

Tuning the tribofilm nanostructures of polymer-on-metal joint replacements for simultaneously enhancing anti-wear performance and corrosion resistance.

Total joint replacement is currently the most successful clinical treatment for improving the life quality of individuals afflicted with end-stage osteoarthritis of knee or hip joints. However, release of wear and corrosion products from the prostheses is a critical issue causing adverse physiological responses of local issues. β-SiC nanoparticles were dispersed into polyetheretherketone (PEEK) materials and their role in tribocorrosion performance of PEEK-steel joints exposed to simulated body fluid was investigated.

[Morphological and pathological changes of larynx after severe laryngeal burn in dogs and their relationship with laryngostenosis].

To investigate the morphological and pathological changes of the larynx after severe laryngeal burn in dogs and their relationship with laryngostenosis. Eighteen healthy, male beagle dogs were assigned into control group, immediately after injury group, and 2, 4, 6, and 8 weeks after injury groups according to the random number table, with 3 dogs in each group. Dogs of injury group inhaled saturated steam through mouth for 5 seconds to reproduce severe laryngeal burn.

[The clinicopathological associations between TGF-β1 and papillary thyroid carcinoma: a Meta-analysis.].

To comprehensively evaluate the association between the positive expression rate of transforming growth factor beta 1 (TGF-β1) and papillary thyroid carcinoma (PTC) by using Meta-analysis.Search the CNKI, Wan fang, VIP and PubMed database for accumulating papers studying on the relationship between the positive expression of TGF-β1 and PTC in Chinese and English. Revman 5.

Switching Brake Materials To Extremely Wear-Resistant Self-Lubrication Materials via Tuning Interface Nanostructures.

Tribological performance of motion components is one of the key aspects that must be considered in a wide range of applications such as vehicles, aircrafts, and manufacturing equipment. This work demonstrates that further addition of only low-loading hard nanoparticles into a formulated nonasbestos organic brake material directly switches its functionality to a self-lubrication material. More importantly, the newly developed nanocomposites exhibit an extremely low wear rate.

One or Two Drains for the Treatment of Surgical Site Infections After Lumbar Spine Surgery.

Background: Optimal drainage after débridement for treating postoperative surgical site infection (SSI) is controversial. We compared single-tube drainage with double-tube drainage.

Methods: We retrospectively analyzed 1125 patients with lumbar degenerative disease who underwent lumbar surgery.

Significance of an in-situ generated boundary film on tribocorrosion behavior of polymer-metal sliding pair.

Polymer composites have a high potential for applications as tribo-materials exposed to sea water owing to their self-lubrication characteristic and high chemical stability. In the present work, tribological behaviors of polyetheretherketone (PEEK) composites rubbing with stainless steel in sea water were explored using a pin-on-disc tribometer integrated with a potentiostat for electrochemical control. It was demonstrated that further adding 5 vol% hexagonal boron nitride (h-BN) nanoparticles into PEEK reinforced with short carbon fibers (SCF) significantly enhanced the wear resistance.

Soft/Hard-Coupled Amphiphilic Polymer Nanospheres for Water Lubrication.

Amphiphilic polymer nanospheres of poly(3-sulfopropyl methacrylate potassium salt- co-styrene) [P(SPMA- co-St)] were prepared by a simple soap-free emulsion polymerization method and used as efficient water lubrication additives to enhance the antiwear behaviors of the TiAlV alloy. The monodisperse and flexible P(SPMA- co-St) bicomponent copolymer nanospheres were synthesized with a controllable manner by adjusting the mass fraction ratio of the monomers, with the hydrophobic polystyrene (PSt) as the hard skeletal carrier component and the hydrophilic PSPMA with a hydration layer structure as the soft lubrication layer in the course of friction. The influences of the monomer concentration, the copolymer nanosphere additive content, the load, and the frequency of the friction conditions on their tribological properties were studied in detail, and a probable antiwear mechanism of the soft/hard-coupled copolymer nanospheres under water lubrication was also proposed.