Preliminary phytochemical screening, antioxidant and antihyperglycaemic activity of Moringa oleifera leaf extracts.

Moringa oleifera plant has been widely used for a vast number of folkloric medicinal purposes. The research aimed to investigate the antioxidant and antihyperglycaemic activity of Moringa oleifera leaf extracts obtained using different solvent systems for extraction. The solvent extracts of Moringa oleifera were: water extract (100% MoWE), 50% Methanolic extract (50% MoME), 100% Methanolic extract (100% MoME), 50% Ethanolic extract (50% MoEE), and 100% Ethanolic extract (100% MoEE).

α-Glucosidase Inhibitory Prenylated Anthranols from Harungana madagascariensis.

Four new prenylated anthranols, harunganols C-F (1-4), along with kenganthranol A (5), harunganin (6), and ferruginin A (7), were identified from the leaves of Harungana madagascariensis. The structures of compounds 2, 5, and 7 were confirmed by single-crystal X-ray diffraction analysis. Compound 1 is a unique symmetrical anthranol dimer connected via a CH2 group.

Evaluation of antioxidant activity of Tetracarpidium conophorum (Müll. Arg) Hutch & Dalziel leaves.

This study evaluated the antioxidant activity as well as bioflavonoid content of the methanol and ethanol-water extracts of the fresh and dried leaves of Tetracarpidium conophorum. Antioxidant activity was determined by spectrophotometric methods using DPPH free radical, nitric oxide radical inhibition and ferric reducing antioxidant power assays. In addition, total phenolics, flavonoids and proanthocyanidin content were also determined.

Homocysteine and folate levels as indicators of cerebrovascular accident.

Background: Homocysteinemia has been established as a risk factor for cardiovascular disorders by the American Heart Association.1 Cerebrovascular accident (stroke) is presently ranked as one of the leading causes of morbidity and mortality worldwide. The aim of this study was to determine homocysteine and folate levels and some basic hematologic parameters in patients who sustain a cerebrovascular accident and those who do not.

Invitro evaluation of the neutralising capacity of twenty brands of antacids in Lagos, Nigeria.

Background: The use of substandard drugs is a great threat to the lives of people in the community. Identification of substandard drugs is important to exclude their use in clinical practice. These drugs may lead to reduced efficacy of pharmacotherapy.

The physicochemical and antibacterial properties of ciprofloxacin-Mg2+ complex.

Purpose: Co-administration of quinolone antibiotics with cation-containing medicaments such as, antacids has been reported to influence the overall bioavailability leading to subtherapeutic plasma concentrations of these antibiotics in humans.

Objectives Of The Study: The present work was designed to evaluate the binding constant, binding molar ratio, influence of temperature on the binding constant of ciprofloxacin-Mg2+ and to determine the antimicrobial activity of ciprofloxacin and ciprofloxacin-Mg2+.

Methods: Job's method of continuous variation and Bonesi-Hildebrand equation were adopted to determine the molar ratio and stability constant respectively.