Effects of Caffeine Ingestion on Pulmonary V˙O2 Kinetics and Muscle Fatigue During Severe-Intensity Cycling Exercise.

Introduction: This study aimed to analyze the effect of caffeine (CAF) intake on pulmonary oxygen uptake (V˙O2) kinetics, muscle fatigue, and physiological and perceptual parameters during severe-intensity cycling exercise.

Methods: Twelve physically active men (age: 26 ± 5 years; V˙O2peak: 46.7 ± 7.

No Combined Effect of Caffeinated Chewing Gum and Priming Exercise on Oxygen Uptake and Muscle Near-Infrared Spectroscopy-Derived Kinetics: A Double-Blind Randomized Crossover Placebo-Controlled Trial in Cyclists.

This study aimed to investigate the effects of caffeine ingestion by chewing gum (GUMCAF) combined with priming exercise on pulmonary oxygen uptake (V˙O2) and near-infrared spectroscopy-derived muscle oxygen extraction (HHb + Mb) kinetics during cycling performed in a severe-intensity domain. Fifteen trained cyclists completed four visits: two under a placebo gum (GUMPLA) and two under GUMCAF ingestion. Each visit consisted of two square-wave cycling bouts at Δ70 intensity (70% of difference between the V˙O2 at first ventilatory threshold and V˙O2max) with duration of 6 min each and 5 min of passive rest between the bouts.

Match-Play Running Performance in Professional Male Soccer Players: The Role of Anaerobic Speed Reserve.

This study aimed to compare match-play running performance between players with a high (H) and low (L) anaerobic speed reserve (ASR) profile in professional soccer players. Thirty-six male players from the same club (age: 23.3 ± 5.

Assemblage Structure of Ichthyoplankton Communities in the Southern Adriatic Sea (Eastern Mediterranean).

Studies based on fish early life stages can provide information on spawning grounds and nursery areas, helping to determine the implications for stock biomass fluctuations of recruitment variability. This study describes the composition, abundance, spatial distribution and differences in day/night vertical distribution of ichthyoplankton in the southern Adriatic Sea. Samples were collected within the framework of the COCONET project (Towards COast to COast NETworks of marine protected areas) from 9 to 18 May 2013 by the , using the electronic multinet EZ-NET BIONESS (Bedford Institute of Oceanography Net Environmental Sampling System).

Customized Series Elastic Actuator for a Safe and Compliant Human-Robot Interaction: Design and Characterization.

When it comes to robotic-mediated rehabilitation it is mandatory to design a system that guarantees a safe and compliant human-machine interaction. Dealing with rehabilitative upper limb exoskeletons, Series Elastic Actuators offer a potential solution for this purpose. This work proposes four different solutions for SEAs' spring design.

Effects of physical training on functional, clinical, morphological, behavioural and psychosocial outcomes in post-COVID-19 infection: COVID-19 and REhabilitation study (CORE-study)-a study protocol for a randomised controlled clinical trial.

Background: The COVID-19 pandemic remains ongoing, with a significant number of survivors who have experienced moderate to severe clinical conditions and who have suffered losses of great magnitude, especially in functional capacity, triggering limitations to daily autonomy and quality of life. Among the possibilities of intervention for disease rehabilitation, physical exercise training stands out, which can benefit several health outcomes and favours the adoption of healthier behaviours. Therefore, the aim of the study will be to analyse the effects of physical training on the functional, clinical, morphological, behavioural and psychosocial status in adults and the elderly following COVID-19 infection.

Energy metabolism and muscle activation heterogeneity explain slow component and muscle fatigue of cycling at different intensities.

New Findings: What is the central question of this study? What are the physiological mechanisms underlying muscle fatigue and the increase in the O cost per unit of work during high-intensity exercise? What is the main finding and its importance? Muscle fatigue happens before, and does not explain, the slow component ( ), but they share the same origin. Muscle activation heterogeneity is associated with muscle fatigue and . Knowing this may improve training prescriptions for healthy people leading to improved public health outcomes.

Visible light-driven degradation of Acid Orange 7 by light modulation techniques.

The impact of light modulation on the decolorization of Acid Orange 7 (AO7) in aqueous solution was examined in this paper. A fixed bed batch photocatalytic reactor with a flat plate geometry, irradiated by 240 white-light LEDs, was used. A successful transfer of visible active photocatalyst (N-TiO) in powder form on a polystyrene (PS) transparent plate was realized.

Observing and modeling long-term persistence of P. noctiluca in coupled complementary marine systems (Southern Tyrrhenian Sea and Messina Strait).

In the Mediterranean Sea, the Strait of Messina (MS) is a very peculiar area, connecting highly different regions and representing a privileged observatory for an early comprehension and assessment of ecosystems shifts. It is hypothesized that the outbreaks observed near the coast of many sites in the Mediterranean Sea may be the result of transport of permanent populations of P. noctiluca in pelagic waters to the coast, caused by specific hydrodynamic conditions.

The Impact of Pre-Exercise Carbohydrate Meal on the Effects of Yerba Mate Drink on Metabolism, Performance, and Antioxidant Status in Trained Male Cyclists.

Introduction: The consumption of yerba mate (YM), a source of antioxidants, in a fasted state increases fatty acid oxidation (FAT) during low-moderate-intensity exercise and improves performance in high-intensity exercise. However, the impact of a pre-exercise carbohydrate (CHO) meal on YM effects during exercise is unknown.

Objective: We investigated the effects of yerba mate drink (YMD) consumed in the fasted state (YMD-F) or after a CHO meal (YMD-CHO) on measurements of metabolism, performance, and blood oxidative stress markers in cycling exercise.

Match activity profile and heart rate responses of top-level soccer referees during Brazilian national first and second division and regional championships.

This study aimed to examine the differences in physical match activities and heart rate (HR) responses experienced by Brazilian field referees (FRs) and assistant referees (ARs) during official matches from and Regional championships. The sample was composed of 51 FRs and 87 ARs. Match activities derived from Global Position System and HR response were collected during official matches.

Post-Match Recovery in Soccer with Far-Infrared Emitting Ceramic Material or Cold-Water Immersion.

We investigated the effects of two common recovery methods; far-infrared emitting ceramic materials (Bioceramic) or cold-water immersion on muscular function and damage after a soccer match. Twenty-five university-level soccer players were randomized into Bioceramic (BIO; n = 8), Cold-water immersion (CWI; n = 9), or Control (CON n = 8) groups. Heart rate [HR], rating of perceived exertion [RPE], and activity profile through Global Positioning Satellite Systems were measured during the match.

Drug repurposing improves disease targeting 11-fold and can be augmented by network module targeting, applied to COVID-19.

This analysis presents a systematic evaluation of the extent of therapeutic opportunities that can be obtained from drug repurposing by connecting drug targets with disease genes. When using FDA-approved indications as a reference level we found that drug repurposing can offer an average of an 11-fold increase in disease coverage, with the maximum number of diseases covered per drug being increased from 134 to 167 after extending the drug targets with their high confidence first neighbors. Additionally, by network analysis to connect drugs to disease modules we found that drugs on average target 4 disease modules, yet the similarity between disease modules targeted by the same drug is generally low and the maximum number of disease modules targeted per drug increases from 158 to 229 when drug targets are neighbor-extended.

Impaired dopamine metabolism is linked to fatigability in mice and fatigue in Parkinson's disease patients.

Fatigue is a common symptom of Parkinson's disease that compromises significantly the patients' quality of life. Despite that, fatigue has been under-recognized as symptom, its pathophysiology remains poorly understood, and there is no adequate treatment so far. Parkinson's disease is characterized by the progressive loss of midbrain dopaminergic neurons, eliciting the classical motor symptoms including slowing of movements, muscular rigidity and resting tremor.

High-Intensity Intermittent Exercise Performed on the Sand Induces Higher Internal Load Demands in Soccer Players.

This study aimed to examine the acute physiological effect of shuttle-run-based high-intensity intermittent exercise (HIIE) performed at the same relative speed (i. e., 100% PS) on sand (SAND) and grass (GRASS) in male junior soccer players.

Similar Time Near VO2max Regardless of Work Rate Manipulation in Cycling Interval Training.

The current study aimed to compare time spent above 90% V̇2max (tV̇2max) during 3 work-matched interval training protocols comprising 8×60-second exercise efforts with decreasing, increasing, or constant work rate distribution within each exercise interval. Ten healthy male subjects (age: 27.6±5.

Heart rate variability kinetics during different intensity domains of cycling exercise in healthy subjects.

The purpose of this study was to verify the heart rate variability (HRV) and heart rate (HR) kinetics during the fundamental phase in different intensity domains of cycling exercise. Fourteen males performed five exercise sessions: (1) maximal incremental cycling test; (2) two rest-to-exercise transitions for each intensity domain, that is, heavy (Δ30) and severe (Δ60) domains. HRV markers (SD1 and SD2) and HR kinetics in the fundamental phase were analyzed by first-order exponential fitting.

Phase Angle Is Related to 10 m and 30 m Sprint Time and Repeated-Sprint Ability in Young Male Soccer Players.

Objective: To examine the association between phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) and components of physical performance in male youth soccer players.

Design: Cross-sectional.

Methods: Sixty-two players from two professional soccer academies were recruited.

A novel treadmill protocol for uphill running assessment: the incline incremental running test (IIRT).

This study aimed to compare the maximal and submaximal aerobic parameters between two incremental running tests, one being horizontal and the other an incline-based test, namely the incline incremental running test (IIRT). Twenty endurance-trained trail runners completed two incremental treadmill tests, until exhaustion. The first test was performed using an incline of 1%, with speed increments.

HIIT Models in Addition to Training Load and Heart Rate Variability Are Related With Physiological and Performance Adaptations After 10-Weeks of Training in Young Futsal Players.

Introduction: The present study aimed to investigate the effects of two high-intensity interval training (HIIT) shuttle-run-based models, over 10 weeks on aerobic, anaerobic, and neuromuscular parameters, and the association of the training load and heart rate variability (HRV) with the change in the measures in young futsal players.

Methods: Eleven young male futsal players (age: 18.5 ± 1.

Modeling the depletion and reconstitution of W': Effects of prior exercise on cycling tolerance.

Thirteen healthy male subjects (age 28 ± 7 years) performed tests for critical power and W' determination and two square-wave high-intensity exercises until exhaustion either with prior very-heavy intensity cycling (EXP) or without (CON). Prior exercise bout induced a depletion of 60 % of W'. After 10 min of recovery, W' reconstitution was not fully achieved (∼ 92 %).