Simulation education utilizing phantom and angle reference guide in pulmonary nodule CT localization.

Objective: The incidence of sub-centimeter pulmonary nodules has been increasing along with the use of low-dose computed tomography (LDCT) as a screening tool for early lung cancer detection. In our institution, pulmonary nodule computed tomography-guided localization (PNCL) is performed preoperatively with the laser angle guided assembly (LAGA), an angle reference device. This study aims to investigate the efficacy of postgraduate education in a phantom simulation of PNCL, with or without LAGA.

Singapore Paediatric Resuscitation Guidelines 2021.

We present the 2021 Singapore Paediatric Resuscitation Guidelines. The International Liaison Committee on Resuscitation's Pediatric Taskforce Consensus Statements on Science and Treatment Recommendations, which was published in October 2020, and the updated resuscitation guidelines from the American Heart Association and European Resuscitation Council, were reviewed and discussed by the committee. These recommendations were derived after deliberation of peer-reviewed evidence updates on paediatric resuscitation and took into consideration the local setting and clinical practice.

Posterior reversible encephalopathy syndrome with a special focus on seizures.

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by headache, seizures, confusion and visual disturbances, as well as potentially reversible neuroimaging findings in most patients after proper treatment. Seizures is one of the most common clinical presentations of PRES. This review summarizes the potential pathophysiology and clinical features of PRES, as well as a multimodal approach to imaging and also briefly discusses the phenomenon of seizures in paediatric population.

A Multi-Agent Platform to Explore Strategies for Age-Friendly Community Projects in Urban China.

Background And Objectives: Although numerous efforts have been made to promote age-friendly communities (AFCs) in urban China, challenges such as the engagement and management of stakeholders, budget constraints, and policy issues remain. This article describes the work of designing a multi-agent platform (MAP) for the briefing stage of AFC projects.

Research Design And Methods: The process to design the MAP is first described, and the components and variables are identified.

Promoting Construction Industrialisation with Policy Interventions: A Holistic Review of Published Policy Literature.

By adopting the concept of 'factory assembly followed by onsite installation,' construction industrialisation (CI) plays an increasingly important role in sustainable urban development. CI can enhance construction quality and efficiency while reducing environmental impacts. To promote the CI, several policy interventions have been developed and implemented in different countries and regions.

A Hybrid Framework for Direct CO Emissions Quantification in China's Construction Sector.

Carbon emission quantifications in China are not consistent, with many standards and methods having been used over the years. This study identified the non-consideration of China-specific technology and databases as a factor limiting comprehensive quantification. The study aimed to comprehensively quantify regional direct CO emission in the industry using a hybrid of economic and environmental data.

Regulatory effects of miR-138 and RUNX3 on Th1/Th2 balance in peripheral blood of children with cough variant asthma.

Objectives: To study the expression levels of microRNA-138 (miR-138) and Runt-related transcription factor 3 (RUNX3) in peripheral blood of children with cough variant asthma (CVA) and their regulatory effects on Th1/Th2 balance.

Methods: Sixty-five children with CVA (CVA group) and 30 healthy children (control group) were enrolled. Peripheral venous blood samples were collected for both groups, and CD4 T cells were isolated and cultured.

Improving Construction Industrialization Practices from a Socio-Technical System Perspective: A Hong Kong Case.

Construction Industrialization (CI) tends to improve industrial performance and contributes substantially towards global sustainability. Considering these merits, many countries and regions, including Hong Kong, have released policies to promote CI uptake. However, those policy interventions ignore the dynamic influence of stakeholders and technologies, which significantly influence the efficient management of CI.

Density functional theory calculations of copper-doped rutile crystals: Local structural, electronic, optical, and electron paramagnetic resonance properties.

The local structural, electronic, optical, and electron paramagnetic resonance (EPR) properties are uniformly studied for Cu -doped rutile (TiO ) crystals by using the density functional theory (DFT) calculations. The local cation-oxygen bond lengths and planar bond angle, band gap, Mulliken charge and overlapping population, density of state (DOS), and UV-Vis absorption spectra are calculated for pure and copper-doped rutile. The smaller overlapping population of Cu-O bonds in the doped system than Ti-O bonds in pure rutile reflects weaker orbital admixtures or covalency of the former.

[Genotype distribution and behavioral risk factor analysis of human papillomavirus infection among Kazak women in Xinjiang Uygur Autonomous Region].

To investigate the prevalence and genotype distribution of high-risk human papillomavirus (HR-HPV) and the correlation between cervical lesions and analyze the risk factors for HR-HPV infection. In June 2018, a population-based study for cervical cancer screening in Tuoli county of Xinjiang Uygur Autonomous Region was conducted. A total of 2 000 Kazak women aged 25-64 years were included in the study.

[Survey on infections among three types of populations in Wuxi City].

Objective: To investigate the seroprevalence of infections among patients with rheumatoid arthritis, malignant tumors and schizophrenia in Wuxi City, so as to provide data support for the control of toxoplasmosis in these patients.

Methods: A total of 205 cases with definitive diagnosis of rheumatoid arthritis, 257 cases with definitive diagnosis of malignant tumors and 235 cases with definitive diagnosis of schizophrenia were recruited, while 250 healthy volunteers served as controls. The demographic features were captured from the study subjects and serum samples were collected.

Unfolding interregional energy flow structure of China's construction sector based on province-level data.

The construction sector is a critical part in achieving energy conservation targets in China, as it accounts for approximately 30% of the annual national energy supply for building construction. Therefore, this study integrates multi-regional input-output analysis and ecological network analysis to track energy fluxes and pathways from the construction sector, aiming to facilitate the configuration of the energy-flow structure and improve understanding of the region's responsibilities. Results of a spatial distribution analysis show that the eastern area of China leads in fossil energy consumption (e.

Next-Generation Sequencing in Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) is lethal, and the majority of patients present with locally advanced or metastatic disease that is not amenable to cure. Thus, with surgical resection being the only curative modality, it is critical that disease is identified at an earlier stage to allow the appropriate therapy to be applied. Unfortunately, a specific biomarker for early diagnosis has not yet been identified; hence, no screening process exists.

[S100 calcium binding protein A16 promotes fat synthesis through endoplasmic reticulum stress in HepG2 cells].

The aim of this study was to investigate the role of S100 calcium binding protein A16 (S100A16) in lipid metabolism in hepatocytes and its possible biological mechanism. HepG2 cells (human hepatoma cell line) were cultured with fatty acid to establish fatty acid culture model. The control model was cultured without fatty acid.

Parental knowledge and beliefs on the use of child car restraints in Singapore: a qualitative study.

Introduction: Road traffic injuries and fatalities represent a significant public health problem. In Singapore, compliance with appropriate child car restraints (CCRs) is poor. We aimed to understand parental knowledge, beliefs and barriers regarding the use of CCRs.

Long noncoding RNA regulates endothelial cell activities associated with coronary artery disease by up-regulating , , and genes.

Coronary artery disease (CAD) is the leading cause of death worldwide. Long noncoding RNAs (lncRNAs) are a class of noncoding transcripts of > 200 nucleotides and are increasingly recognized as playing functional roles in physiology and disease. is an lncRNA gene mapped to the chromosome 9p21 genetic locus for CAD identified by the first series of genome-wide association studies (GWAS).

[Intramedullary nailing combined with cannulated screw in treating femoral condyles fractures].

Objective: To observe the clinical effects of retrograde intramedullary nailing and cannulated screws in the treatment of femoral condylar fracture.

Methods: From June 2009 to June 2015, 13 patients with femoral condyles fracture were treated by retrograde intramedullary nailing and cannulated screws including 6 males and 7 females with an average age of 46.1 years old ranging from 16 to 76 years old.

[Biomechanical analysis of the correlation between sacral tilt displacement and L₅S₁ disc degeneration].

Objective: To biomechanical analysis of the correlation between sacral tilt displacement and L₅-S₁ disc degeneration.

Methods: From July 2011 to July 2013, 81 patients with lumbar disc herniation and sacroiliac joint disorder including 45 males and 36 females with an average age of (45.39±1.

Immune system activation in the pathogenesis of posterior reversible encephalopathy syndrome.

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome characterized by a variable combination of headaches, seizures, altered mental status, visual impairment, focal neurological signs and symmetric vasogenic edema in bilateral posterior cerebral circulation territory. The pathogenesis of PRES is still controversial. Most of the clinical conditions associated with PRES involve a systemic toxicity response in the entire organism with activation of the cells of the immune system and cytokines.

[Biomechanical analysis on the correlation between iliac rotation displacement and L(4,5) disc degeneration].

Objective: To study the biomechanical relationship between iliac rotation displacement and L(4,5) disc degeneration, and to provide clinical evidences for the prevention and treatment of L(4,5) disc degeneration and herniation.

Methods: From March 2012 to February 2014,68 patients with lumbar disc herniation combined with sacroiliac joint disorders were selected. Among them, 42 patients with L(4,5) disc herniation combined with sacroiliac joint disorders included 22 males and 20 females, ranging in age from 19 to 63 years old, with an average of (51.

Biomechanical effects of morphological variations of the cortical wall at the bone-cement interface.

Background: The integrity of bone-cement interface is very important for the stabilization and long-term sustain of cemented prosthesis. Variations in the bone-cement interface morphology may affect the mechanical response of the shape-closed interlock.

Methods: Self-developed new reamer was used to process fresh pig reamed femoral canal, creating cortical grooves in the canal wall of experimental group.

Improving Management of Green Retrofits from a Stakeholder Perspective: A Case Study in China.

Green retrofits, which improve the environment and energy efficiency of buildings, are considered a potential solution for reducing energy consumption as well as improving human health and productivity. They represent some of the riskiest, most complex, and most uncertain projects to manage. As the foundation of project management, critical success factors (CSFs) have been emphasized by previous research.