Association between autoimmune pancreatitis and ulcerative colitis: a report of 12 patients.

Introduction: pancreatic manifestations in inflammatory bowel disease (IBD) mainly include acute pancreatitis secondary to drugs and, less frequently, autoimmune pancreatitis, in particular type 2 autoimmune pancreatitis.

Methods: retrospective study of patients diagnosed with ulcerative colitis (UC) and autoimmune pancreatitis (AIP) in control at two centers in Santiago, Chile, between 2007 and 2018. Clinical data, laboratory results, images and response to treatment were recorded.

Alopecic and Aseptic Nodules of the Scalp: First Report in South America and Second in America.

Alopecic and aseptic nodules of the scalp, also named pseudocysts of the scalp, are a relatively new, little-known, and for sure underdiagnosed disease. It affects mostly young men and is characterized by a solitary or a few dome-shaped nodules accompanied by nonscarring alopecia, deep inflammatory infiltration in the skin biopsy specimen, and, in most cases, granulomas. It has a good response to doxycycline, intralesional corticosteroids, or drainage/aspiration of the lesion.

Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study.

Objectives: The long-term safety of exposure to anti-tumor necrosis factor (anti-TNFα) drugs during pregnancy has received little attention. We aimed to compare the relative risk of severe infections in children of mothers with inflammatory bowel disease (IBD) who were exposed to anti-TNFα drugs in utero with that of children who were not exposed to the drugs.

Methods: Retrospective multicenter cohort study.

Immunological Changes in Blood of Newborns Exposed to Anti-TNF-α during Pregnancy.

Background: Although anti-TNF-α monoclonal antibodies are considered safe during pregnancy, there are no studies on the development of the exposed-infant immune system. The objective was to study for the first time the impact of throughout pregnancy exposure to anti-TNF-α has an impact in the development of the infant's immune system, especially B cells and the IL-12/IFN-γ pathway.

Methods: Prospective study of infants born to mothers with inflammatory bowel disease treated throughout pregnancy with anti-TNF-α (adalimumab/infliximab).

Cystic Lesions in Autoimmune Pancreatitis.

Autoimmune pancreatitis (AIP) can be chronic or recurrent, but frequently completely reversible after steroid treatment. A cystic lesion in AIP is a rare finding, and it can mimic a pancreatic cystic neoplasm. Difficulties in an exact diagnosis interfere with treatment, and surgery cannot be avoided in some cases.

[Mortality of acute pancreatitis in a 20 years period].

Background: Mortality for acute pancreatitis (AP) in Chile has fluctuated between 7 ana 10% in last years.

Aim: To evaluate AP mortality over a period of 20 years in a clinical hospital in Santiago, Chile.

Material And Methods: Review of the database of hospital discharges with the diagnosis of acute pancreatitis, between 1990 and 2010 and the medical records of those patients.

[Ménétrier disease. Report of one case].

Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight loss and hypoalbuminemia. Diffuse hypertrophic gastric folds, elevated ulcerated sessile lesions and focal duodenal involvement were seen at endoscopy.

[Bedside index for severity in acute pancreatitis (BISAP) score as predictor of clinical outcome in acute pancreatitis: retrospective review of 128 patients].

Background: Identification of patients at risk for severe disease early in the course of acute pancreatitis (AP) is essential to optimize management and to improve outcomes.

Aim: To assess BISAP score as a predictor of severity of AP.

Patients And Methods: Retrospective review of AP patients between January 2009 and December 2010.

[Emergency of vancomycin-resistant Enterococcus infections in a teaching hospital in Chile].

An active surveillance of vancomycin-resistant enterococci (VRE) intestinal colonization in selected group of patients has been developed in Chile since year 2000. Nevertheless, no reports of clinical cases have been published. Aim.