Thermal Characterization and Heat Capacities of Seven Polyphenols.

Polyphenolic compounds are key elements in sectors such as pharmaceutics, cosmetics and food; thus, their physicochemical characterization is a vital task. In this work, the thermal behavior of seven polyphenols (-resveratrol, -polydatin, kaempferol, quercetin, myricetin, hesperidin, and (-)-epicatechin) was investigated with DSC (differential scanning calorimetry) and TGA (thermogravimetric analysis). Melting temperatures, enthalpies of fusion and decomposition temperatures were determined, and heat capacities were measured in the temperature range from 283.

Artificial intelligence-driven analysis of embryo morphokinetics in singleton, twin, and triplet pregnancies.

In recent years, the transfer of more than one embryo has become less frequent to diminish multiple pregnancies. Even so, there is still a risk of one embryo splitting into two or even three. This report presents the case of a triamniotic monochorionic gestation in a 35-year-old woman, obtained after the transfer of a single day 5 embryo that had been previously hatched with a laser and subsequently transferred in a fresh IVF cycle.

A proposal of a fecal scoring system based on physicochemical analyses of suckling pig feces.

Background: Digestive disorders are one of the main health problems in suckling piglets. The correct visual identification of feces in suckling piglets is an important tool for the diagnosis of enteric diseases. The aim of the present observational study was to analyze different physicochemical parameters of the feces of suckling piglets aged 0 to 21 days: visual appearance (color and consistency), fecal dry matter (FDM) content and pH.

Oral Herpes Simplex Virus Mimicking Tongue Squamous cell Carcinoma in Von Hippel-Lindau Patient: A Case Image.

We present the case of a 51-year-old man with Von Hippel-Lindau disease and a history of renal transplantation who developed a persistent, painful tongue lesion with episodes of significant swelling. Given his history of prolonged immunosuppression and elevated cancer risk, oral squamous cell carcinoma was a major concern. However, histopathological evaluation confirmed recrudescent herpes simplex virus (HSV) infection rather than malignancy.

Simulation training with haptic feedback of instrument vibrations reduces resident workload during live robot-assisted sleeve gastrectomy.

Background: New surgeons experience heavy workload during robot-assisted surgery partially because they must use vision to compensate for the lack of haptic feedback. We hypothesize that providing realistic haptic feedback during dry-lab simulation training may accelerate learning and reduce workload during subsequent surgery on patients.

Methods: We conducted a single-blinded study with 12 general surgery residents (third and seventh post-graduate year, PGY) randomized into haptic and control groups.

From Bystander-to-Upstander: A Novel Intervention Framework to Address Microaggressions in a Pediatric Academic Medical Center.

Microaggressions undermine health professionals' performance in patient care, research, and education. This study aimed to develop and evaluate an intervention addressing microaggressions in healthcare settings by empowering bystanders to act as upstanders across an academic medical center (AMC). This was achieved through an educational intervention that included a novel framework, didactics, video demonstrations, and practice with realistic scenarios.

Physical and Surface Chemical Analysis of High-Quality Antimicrobial Cotton Fabrics Functionalized with CuO Grown from Different Copper Salts: Experimental and Theoretical Approach.

The emergence of harmful microorganisms poses a public health challenge. Antimicrobial cotton textiles with semiconductor oxides offer a promising solution to mitigate pathogen spread. Here, we study the physicochemical interactions between copper oxides (CuO) and cellulose in cotton fiber functionalized with these same oxides for antimicrobial properties.

Enhancing cardiovascular patients' knowledge of air pollution: a pilot study evaluating the impact of an educational intervention in cardiac rehabilitation.

Introduction: Air pollution poses significant risks to cardiovascular health, yet patients often lack comprehensive knowledge about its impact and mitigation strategies. This study aims to evaluate the effectiveness of an educational intervention within a cardiac rehabilitation (CR) context in enhancing patients' understanding of air pollution and its cardiovascular effects.

Methods: A pre-post pilot study was conducted from February 2021 to June 2021 at the Gregorio Marañón University General Hospital, Madrid, Spain.

Pulmonary fibrosis in patients with autoimmune pulmonary alveolar proteinosis: a retrospective nationwide cohort study.

Background: Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease that may progress towards pulmonary fibrosis. Data about fibrosis prevalence and risk factors are lacking.

Methods: In this retrospective multicentre nationwide cohort, we included patients newly diagnosed with aPAP between 2008 and 2018 in France and Belgium.

Visual attention and recall of flavored cigarillo package elements among young adults: A randomized control trial.

Introduction: Flavoring in cigarillos contributes to greater product initiation and abuse liability particularly among young adults. Few studies have examined how packaging elements, including flavor, may draw visual attention from potential consumers as well as impact product recall. This study aimed to test the difference in visual attention to flavor names and other packaging elements on cigarillo products as well as recall of these packaging elements.

Protection over restoration to ensure water sustainability.

Plastics pollution, persistent chemical contamination and inadequately treated wastewater are three key aspects that hinder access to safe and affordable water for all. We argue that a strong priority on pollution avoidance, research for remediation, and tighter regulation and monitoring must be implemented to make progress.

Impact of Dilute DIO Additive on Local Microstructure of Fluorinated, pNDI-Based Polymer Solar Cells.

The performance of all-polymer solar cells is often enhanced by incorporating solvent additives during solution processing. In particular, blends based on the model all-polymer system PBDBT:N2200 have been shown to have increased short-circuit current and fill factor when processed with dilute diiodooctane (DIO). However, the morphological mechanism that drives the increase in performance is often not well understood due to limitations in common characterization techniques.

Optical frequency filtering for Raman beams.

We present an optical filter that is appropriate for use with Raman beams in atomic interferometry. This is a filter that lets the light of the two frequencies of the Raman pair go through and rejects spurious frequencies that may be close to the atomic resonance and cause decoherence. We characterized the filter's performance optically and also by shining the light into atoms in a Ramsey sequence, to look for decoherence effects from photon scattering.

Epithelial-Mesenchymal Plasticity and Epigenetic Heterogeneity in Cancer.

The tumor microenvironment comprises various cell types and experiences dynamic alterations in physical and mechanical properties as cancer progresses. Intratumoral heterogeneity is associated with poor prognosis and poses therapeutic challenges, and recent studies have begun to identify the cellular mechanisms that contribute to phenotypic diversity within tumors. This review will describe epithelial-mesenchymal (E/M) plasticity and its contribution to phenotypic heterogeneity in tumors as well as how epigenetic factors, such as histone modifications, histone modifying enzymes, DNA methylation, and chromatin remodeling, regulate and maintain E/M phenotypes.

Uterine window and placenta accreta spectrum in a dichorionic, diamniotic twin gestation complicated by postpartum hemorrhage.

Cesarean scar defects encompass a spectrum of separation of the uterine layers that increase risk of uterine rupture during labor and delivery. When coupled with the presence of placenta accreta spectrum, a condition characterized by abnormal adherence to or invasion of the myometrium by the placenta, the risk of life-threatening hemorrhage significantly increases. As rates of cesarean delivery increase, it is important to understand the imaging findings typical of both conditions.

Invasive procedures and surgery following etranacogene dezaparvovec gene therapy in people with hemophilia B.

Background: Little information regarding the management of invasive procedures in people with hemophilia B (HB) after undergoing gene therapy is available. Here, we report the management of invasive procedures in people with severe or moderately severe HB who had previously been treated with etranacogene dezaparvovec in the phase 2b and phase 3 Health Outcomes with Padua Gene; Evaluation in Hemophilia B clinical trials (NCT03489291 and NCT03569891).

Objectives: The objective of this study was to describe the use of exogenous FIX, endogenous FIX activity prior to invasive procedures, and peri- and postoperative bleeds in participants who underwent invasive procedures after receiving etranacogene dezaparvovec gene therapy.

A Systematic Evaluation for Oropharyngeal Dysphagia in Non-institutionalized Elderly Patients with Home Care-based in the Community.

Oropharyngeal Dysphagia (OD) increases the risk of hospitalization and the use of health services; however, it is often detected and studied in institutionalized patients with limited attention given to the community. The aim of this study was to determine the prevalence of OD and its associated factors after conducting a program consisting of a systematic assessment of OD for in patients living independently in their dwellings and requiring home-based care. We conducted a cross-sectional study involving a systematic assessment of disabled and elderly patients enrolled in a home-based primary care program at three urban centers (Barcelona, Spain).

Mediterranean mussels (Mytilus galloprovincialis) exposure to fluoxetine: Bioaccumulation and biotransformation products.

The significant rise in antidepressant consumption in recent years was accentuated by COVID-19 pandemic. Among these antidepressant, fluoxetine, a selective serotonin re-uptake inhibitor (SSRI), is the most prescribed worldwide. The present study investigated its bioaccumulation and metabolization in the mussel Mytilus galloprovincialis, generally recognized as a reliable bioindicator for assessing environmental quality and the accumulation of various contaminants.