Occupational medicine in a developing society: a case study of Venezuela.

Recent activities of the World Health Organization and other international agencies have placed new emphasis on occupational health in developing nations. Venezuela is a nation in transition from a developing society dominated economically by petroleum and agriculture to an economically-diversified industrialized urban society. It provides a case study which illuminates the problems of extending occupational health services in developing economies and questions of public policy regarding utilization of medical resources and the priority that occupational health should hold in such a society.

Hemodynamic and excretory response of the neonatal canine kidney to acute volume expansion.

It is generally recognized that developing animals retain sodium due to an enhanced reabsorption in distal tubule segements, even when the amount administered is in excess of their needs. This study was designed to test the relationship between this relative inability to dispose of a saline load and the functional characteristics of the kidney during postnatal maturation. In addition, we explored the role played by some of the factors known to affect natriuresis in the adult subject.

Evaluation of infants and children for kidney disease.

An attempt is being made to provide a logical framework for the differential diagnosis of kidney disease in children. The process is facilitated by the fact that the starting points heralding renal disease are rather limited, the great majority of the conditions presenting themselves as one of five signs or five syndromes. Within each of these categories a sequential approach permits passage from the most common diseases and innocuous methods of clinical investigation to more esoteric entities and invasive techniques.

Atherogenesis in swine fed several types of lipid-cholesterol diets.

Eighteen-month-old Nebraska strain minipigs were fed diets containing 2% cholesterol and 20% corn oil, lard, or coconut oil for 12 to 18 months. Concentrations of serum total lipid, total cholesterol, and total phospholipid increased 200 to 300% with each diet. Changes in serum concentrations of Sf 20+ and Sf 0-20 lipoproteins varied with diets fed.

Neonatal changes in renal blood flow distribution in puppies.

The intrarenal distribution of blood flow was studied in 31 newborn mongrel puppies from 18 h to 70 days using xenon washout and krypton autoradiography. Mean renal blood flow increased from 0.39 plus or minus 0.