Patient Radiation Exposure Associated With the Use of Computer Navigation During Spinal Fusion.

Background: Calibration of computer navigation for spinal fusion is most commonly conducted using either a preoperative computed tomography (CT) scan or intraoperative O-arm scanning. This study aimed to directly compare patient radiation exposure from intraoperative O-arm use for pedicle screw placement versus typical diagnostic lumbar spine CT studies.

Methods: A retrospective review of patients undergoing O-arm navigated lumbar spine fusion procedures was performed to record radiation exposure as the primary outcome, as well as surgical and demographic details.

The Use of Spinal Cord Stimulation/Neuromodulation in the Management of Chronic Pain.

Chronic pain causes a tremendous burden on the society in terms of economic factors and social costs. Rates of spinal surgery, especially spinal fusion, have increased exponentially over the past decade. The opioid epidemic in the United States has been one response to the management of pain, but it has been fraught with numerous catastrophic-related adverse effects.

Management of Sacroiliac Joint Pain.

Sacroiliac joint (SIJ)-based pain can be difficult to diagnose definitively through physical examination and conventional radiography. A fluoroscopically guided injection into the SIJ can be both diagnostic and therapeutic. The initial phase of treatment involves nonsurgical modalities such as activity modification, use of a sacroiliac (SI) belt, NSAIDs, and physical therapy.

Abnormalities in gamma-band responses to language stimuli in first-degree relatives of children with autism spectrum disorder: an MEG study.

Background: Synchronous neural oscillatory activity in the gamma range (30-80 Hz) has been shown to be abnormal in individuals with autism spectrum disorders (ASD) and their first-degree relatives in response to simple auditory stimuli. Gamma-band abnormalities in ASD probands have been seen in response to language stimuli, but this has not been investigated in first-degree relatives. This is of particular interest given that language impairments are a core symptom of ASD and may be part of the broad autism phenotype (BAP) seen in relatives.

Not all analogies are created equal: Associative and categorical analogy processing following brain damage.

Current research on analogy processing assumes that different conceptual relations are treated similarly. However, just as words and concepts are related in distinct ways, different kinds of analogies may employ distinct types of relationships. An important distinction in how words are related is the difference between associative (dog-bone) and categorical (dog-cat) relations.

From novel to familiar: tuning the brain for metaphors.

Metaphors are fundamental to creative thought and expression. Newly coined metaphors regularly infiltrate our collective vocabulary and gradually become familiar, but it is unclear how this shift from novel to conventionalized meaning happens in the brain. We investigated the neural career of metaphors in a functional magnetic resonance imaging study using extensively normed new metaphors and simulated the ordinary, gradual experience of metaphor conventionalization by manipulating participants' exposure to these metaphors.

Deconstructing events: the neural bases for space, time, and causality.

Space, time, and causality provide a natural structure for organizing our experience. These abstract categories allow us to think relationally in the most basic sense; understanding simple events requires one to represent the spatial relations among objects, the relative durations of actions or movements, and the links between causes and effects. The present fMRI study investigates the extent to which the brain distinguishes between these fundamental conceptual domains.

Stimulus design is an obstacle course: 560 matched literal and metaphorical sentences for testing neural hypotheses about metaphor.

Despite the ubiquity and importance of metaphor in thought and communication, its neural mediation remains elusive. We suggest that this uncertainty reflects, in part, stimuli that have not been designed with recent conceptual frameworks in mind or that have been hampered by inadvertent differences between metaphoric and literal conditions. In this article, we begin addressing these shortcomings by developing a large, flexible, extensively normed, and theoretically motivated set of metaphoric and literal sentences.

MEG detection of delayed auditory evoked responses in autism spectrum disorders: towards an imaging biomarker for autism.

Motivated by auditory and speech deficits in autism spectrum disorders (ASD), the frequency dependence of superior temporal gyrus (STG) 50 msec (M50) and 100 msec (M100) neuromagnetic auditory evoked field responses in children with ASD and typically developing controls were evaluated. Whole-cortex magnetoencephalography (MEG) was obtained from 17 typically developing children and 25 children with ASD. Subjects were presented tones with frequencies of 200, 300, 500, and 1,000 Hz, and left and right STG M50 and M100 STG activity was examined.

Prescribed spatial prepositions influence how we think about time.

Prepositions combine with nouns flexibly when describing concrete locative relations (e.g. at/on/in the school) but are rigidly prescribed when paired with abstract concepts (e.

Beyond laterality: a critical assessment of research on the neural basis of metaphor.

Metaphors are a fundamental aspect of human cognition. The major neuropsychological hypothesis that metaphoric processing relies primarily on the right hemisphere is not confirmed consistently. We propose ways to advance our understanding of the neuropsychology of metaphor that go beyond simple laterality.

Neural correlates of metaphor processing: the roles of figurativeness, familiarity and difficulty.

There is currently much interest in investigating the neural substrates of metaphor processing. In particular, it has been suggested that the right hemisphere plays a special role in the comprehension of figurative (non-literal) language, and in particular metaphors. However, some studies find no evidence of right hemisphere involvement in metaphor comprehension (e.

Absence of M100 source asymmetry in autism associated with language functioning.

Various clinical populations display atypical volume asymmetry of language structures and also the auditory M100 source. Although such atypical volume asymmetries have also been observed in autism, M100 source asymmetries have not yet been investigated. We examined M100 asymmetry in autism and its relationship with language functioning.

Impairments in phonological processing and nonverbal intellectual function in parents of children with autism.

Language difficulties have been implicated to be a part of the broad autism phenotype in first-degree relatives of individuals with autism. Phonological processing difficulties in particular have been reported by some, but not all groups studying parents or siblings of probands with autism. In the present study, we examined a broad battery of language tasks and general cognitive abilities in parents of children with autistic disorder.

Electrophysiological signatures: magnetoencephalographic studies of the neural correlates of language impairment in autism spectrum disorders.

While magnetoencephalography (MEG) is of increasing utility in the assessment of pediatric patients with seizure disorders, this reflects only a part of the clinical potential of the technology. Beyond epilepsy, a broad range of developmental psychiatric disorders require the spatial and temporal resolution of brain activity offered by MEG. This article reviews the application of MEG in the study of auditory processing as an aspect of language impairment in children.

Incidental learning of abstract rules for non-dominant word orders.

One way in which adult second language learners may acquire a word order that differs from their native language word order is through exposure-based incidental learning, but little is known about that process and what constrains it. The current studies examine whether a non-dominant word order can be learned incidentally, and if so, whether the rule can be generalized to new words not previously seen in the non-dominant order. Two studies examined the incidental learning of rules underlying the order of nouns and verbs in three-word strings.

Anatomic mapping and evaluation of the esophagus in relation to the cervical vertebral body.

The relationship of the esophagus to the cervical vertebral body (CVB), disc space and longus colli (LC) muscles, to our knowledge, has not been previously studied. The purpose of this study was to quantify the relationship of the esophagus to the CVB, disc space and LC. 30 patients were selected for a retrospective review of computed tomography (CT) scans.

Right hemisphere metaphor processing? Characterizing the lateralization of semantic processes.

Previous laterality studies have implicated the right hemisphere in the processing of metaphors, however it is not clear if this result is due to metaphoricity per se or another aspect of semantic processing. Three divided visual field experiments varied metaphorical and literal sentence familiarity. We found a right hemisphere advantage for unfamiliar sentences containing distant semantic relationships, and a left hemisphere advantage for familiar sentences containing close semantic relationships, regardless of whether sentences were metaphorical or literal.

A voxel-based morphometry study of gray matter in parents of children with autism.

Previous structural imaging studies of autistic individuals have identified gray matter abnormalities. It remains unclear, however, which abnormalities contribute to the etiology of autism and, among these abnormalities, which reflect genetic factors. Using voxel-based morphometry, we compared regional gray matter volume in 23 parents of autistic children to an age and sex-matched control sample.

Knee injury in patients experiencing a high-energy traumatic ipsilateral hip dislocation.

Background: Traumatic hip dislocation results from the dissipation of a large amount of energy about the hip joint. Clinically, these forces often are first transmitted through the knee en route to the hip. It is therefore logical to look for coexistent ipsilateral knee injury in patients with a traumatic hip dislocation.

Reproducibility and reliability of the anatomic axis of the lower extremity.

Two observers measured the tibiofemoral angle of 60 knees on hip-knee-ankle and anteroposterior (AP) knee radiographs and repeated the measurements 6 months later. Intraobserver reproducibility was moderate. Interobserver reliability was poor.

Pretreatment with SR48692 has different effects on central neurotensin-induced gastric mucosal defense and inhibition of gastric acid secretion in rats.

Neurotensin is a tridecapeptide present in the brain and gastrointestinal tract. Administration of neurotensin into the brain results in responses in the gastrointestinal tract, suggesting a role for neurotensin in the interrelationships that comprise the brain-gut axis. Intracerebroventricular (i.

Hereditary syndactyly in Angus cattle.

Twenty-five syndactylous Angus cattle, characterized pathologically, were reported from 16 herds in 10 states from 1979 to 1994. Twenty-one (84%) had all 4 legs syndactylous, 3 (12%) had 3 legs syndactylous, and 1 (4%) had 2 legs syndactylous. All syndactylous cattle walked with considerable difficulty.