Aminoacidemias: effects on maze performance and cerebral serotonin.

The feeding of high dietary supplements of L-phenylalanine (7 percent) and L-leucine (7 percent) to weanling rats is associated with poor performance in a multiple-T, water-escape maze. Supplements high in L-tryptophan (5 percent), on the other hand, result in maze performance which is superior to that of controls. Adding 5 percent tryptophan to the high-phenylalanine diet reverses the behavioral deficit.

5-HYDROXYTRYPTAMINE IN SINGLE NEOPLASTIC MAST CELLS: A MICROSCOPIC SPECTROFLUOROMETRIC STUDY.

5-Hydroxytryptamine, catecholamines, and histamine in mast cells can be distinguished by fluorescence microscopy. Microscopic spectrofluorometry can be used to estimate 5-hydroxytryptamine in single neoplastic mast cells grown in vitro, and to study the effect of reserpine on these cells.