[The immunological aspects of chronic pancreatitis].

The immunological status was investigated in 200 patients with chronic pancreatitis. Recurrent pancreatitis was characterized by marked autosensitization to pancreatic tissue, latent pancreatitis forms--by a high level of immune complexes and blood serum immunoglobulins, the painful form--by minimal resistance disorders. Established were clinico-immunological parallels between the frequency of exacerbations and degree of autosensitization, level of immune complex and yield of enzymes.

[The prognostic value of immunologic indices in chronic pancreatitis].

Analysis of clinical and immunologic parallels in 200 patients with chronic pancreatitis has revealed that lymphocyte autosensitization to pancreatic tissue in the lymphocyte blastogenesis test (LBGT) is in high correlation with the frequency of the disease recurrences, and the severity of pancreatic exocrine insufficiency with the immune complex level. This permits recommending LBGT with pancreatic tissue antigen for the prediction of the condition recurrences, and measurements of the immune complexes level for the prediction of the developing exocrine pancreatic insufficiency.