Publications by authors named "GENTON N"

Purpose: We establish renal function and renal reserve capacity in the long-term followup of unilateral nephrectomy in childhood.

Materials And Methods: We recalled 37 subjects who underwent unilateral nephrectomy during childhood (age less than 16 years) to determine glomerular filtration rate, renal plasma flow and functional renal reserve capacity after oral protein loading. Interval since nephrectomy was 0.

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After having practiced two-stage esophagoplasties by retrosternal Iso-peristaltic colic transplant since 1966, we introduced the one-stage procedure in 1989, placing the transplant in the posterior mediastinum following a closed-chest esophagectomy. We have performed 121 such esophagoplasties in children until now. To evaluate the possible effects of the different techniques as accurately as possible, we recorded two uniform series of 32 and 41 esocoloplasties carried out under identical conditions by two operators respectively.

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The purpose of this report is to assess the role of long-term clinical and hepatic ultrasound (US) follow-up in children who sustained blunt liver trauma. Forty-three children with blunt hepatic injury were prospectively studied between 1976 and 1994 in our institution. Four patients died (9%).

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Between 1970 and 1985, we count 32 children with compressive fractures of the vertebral column. None of them undergo a surgical procedure. We examine 24 of these 32 children with a mean delay of 10.

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A six-year old boy presented with prolonged unexplained fever caused by an infected teratoma of the lower posterior mediastinum. Modern imaging, combining ultrasonography with computed tomography, enabled the correct diagnosis of topography, extension and nature of this rare lesion to be made and explained the clinical features. Follow-up CT showed regression of the abscess after antibiotics thus permitting elective surgery.

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Upper urinary tract function was evaluated in 15 infants in whom urethral valves were diagnosed. One baby died at 16 days of age and was not completely investigated. In 4, the valves did not have untoward effect on the bladder and the upper urinary tract.

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Thoracic trauma is uncommon in children. It should not be managed any more as adult's trauma. We present our experience with 85 children form 1 to 16 years of age, presenting severe thoracic trauma treated in Lausanne, Switzerland, between 1976 and 1990.

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This study relates the postoperative evolution after ureterovesical reimplantation for vesicoureteral reflux (VUR) in 141 children who were ten years old or younger at the time of surgery. Renal growth and morphology were evaluated 2 and 5 years after surgery. We estimated renal growth by measuring the ratio of the bipolar parenchymal thickness to the total length of the kidney.

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Of 141 children undergoing surgery for vesicoureteral reflux detected by voiding cystourethrography, preoperative excretory urography demonstrated signs suggestive of vesicoureteral reflux in 154 (67.5%) of 228 refluxing ureter. In 48 refluxing ureters (21%) renal growth retardation was the only sign; the latter was appreciated by applying the index described by Hodson, that is, the ratio of bipolar parenchymal thickness to total renal length.

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We report our results of a retrospective study of vesico-ureteral reflux based on the families of 66 index patients. The recurrence risk for sibs is 9,3%. With a prospective approach (ultrasound and uroradiology), the proportion of affected sibs is 26,6%.

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Long-term functional renal study of 41 patients with severe congenital urinary tract malformations. The main factor for prognosis is the stage of renal lesions when a surgical treatment is applied.

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A 141 children study: Clinical study of 141 children less than 10 years old with vesico-ureteric reflux. No specific associated birth defects was noted.

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Follow-up study of 141 cases of vesico-ureteric reflux (less than 10 years old) treated by Cohen's method. Computerized study, 5 years after treatment, with analysis of the influence of different parameters (type of VUR, age, sex, urinary infection or not, space of time between diagnosis and treatment) on the renal parenchymal radiographic measurements ( Hodson 's method). The youngest is the child when he is treated, the best is the functional result.

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The dissection and Vossschulte ligature of the esophagus, modified by Rehbein, is precisely directed on the oesophageal varices, responsible for the most dangerous symptom of portal hypertension in childhood. This technic was employed six times between 1974 and 1977 in the prehepatic portacaval obstructions. The postoperative follow-up actually carries over a period from 5 to 8 years without any hemorrhage recurrency.

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Radiological study of conjoined thoracopagus twins. The digestive and biliary tracts, the urinary and cardiovascular systems have been examined. The problems and difficulties encountered in the various procedures and in the interpretation of their results are described.

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Eight children with high or intermediate anorectal malformations and fecal incontinence after primary repair were operated according the Pickrell technique. In 3 patients, the result of the Pickrell plasty was clinically not sufficient and the opposite gracilis muscle was used in addition at a second operative session. The 8 children were studied clinically, radiologically, by electromyography and manometry.

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An attempt was made to separate 7-wk-old conjoined twins. It proved unsuccessful because of extensive cardiac malformations in the shared heart. Details of operation and postmortem findings are described.

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A unique case of a prepubertal XX male with profound mental and physical retardation, retinitis pigmentosa, ambiguous genitalia and multiple congenital anomalies is reported. His clinical, genetic, dermatoglyphic and histological findings are presented. This case could represent a new multiple congenital malformation syndrome.

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4 years of experience in the rehabilitation of neurogenic bladders by endovesical electrostimulation (ES) with 31 children permits us to judge the value and limitations of this treatment. 8 children (26%) reacted favorably to treatment and acquired continence approaching normal. 12 children (38%) showed modifications of bladder-sphincter equilibrium, without acquiring socially sufficient continence.

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