Head-mounted eye tracker videos and raw data collected during breathing recognition attempts in simulated cardiac arrest.

This paper presents data collected by Pedrotti et al. (2022, 2024) [1,2], which includes videos captured using a Dikablis head-mounted eye tracker (Ergoneers GmbH, Germany), along with the corresponding raw data. The data collection aimed to assess participants' ability to recognize breathing in a simulated cardiac arrest scenario.

Long-term ecological assessment of intracranial electrophysiology synchronized to behavioral markers in obsessive-compulsive disorder.

Detection of neural signatures related to pathological behavioral states could enable adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for neurological and psychiatric disorders. This approach requires identifying neural biomarkers of relevant behavioral states, a task best performed in ecologically valid environments. Here, in human participants with obsessive-compulsive disorder (OCD) implanted with recording-capable DBS devices, we synchronized chronic ventral striatum local field potentials with relevant, disease-specific behaviors.

Visual Fixation on the Thorax Predicts Bystander Breathing Detection in Simulated Out-of-Hospital Cardiac Arrest, but Video Debriefing With Eye Tracking Gaze Overlay Does Not Enhance Postallocation Success Rate: A Randomized Controlled Trial.

Introduction: Bystander cardiopulmonary resuscitation in out-of-hospital cardiac arrest is associated with higher survival rates. Even trained health care staff cannot assess breathing well enough to detect cardiac arrest. Recognition of cardiac arrest by lay rescuers might be overlooked in adult basic life support resuscitation guidelines, which explain what to do, but not how to do it.

Honeycomb: a template for reproducible psychophysiological tasks for clinic, laboratory, and home use.

Objective: To improve the ability of psychiatry researchers to build, deploy, maintain, reproduce, and share their own psychophysiological tasks. Psychophysiological tasks are a useful tool for studying human behavior driven by mental processes such as cognitive control, reward evaluation, and learning. Neural mechanisms during behavioral tasks are often studied via simultaneous electrophysiological recordings.

Identifying Herbal Adverse Events From Spontaneous Reporting Systems Using Taxonomic Name Resolution Approach.

The efficacy and safety of herbal supplements suffer from challenges due to non-uniform representation of ingredient terms within biomedical and observational health data sources. The nature of how supplement data are reported within Spontaneous Reporting Systems (SRS) can limit analyses of supplement-associated adverse events due to the use of incorrect nomenclature or failing to identify herbs. This study aimed to extract, standardize, and summarize supplement-relevant reports from two SRSs: (1) Food and Drug Administration Adverse Event Reporting System (FAERS) and (2) Canada Vigilance Adverse Reaction (CVAR) database.

Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.

Metformin is considered the first-line treatment for type 2 diabetes. While metformin primarily increases insulin sensitivity, evidence also suggests that metformin affects the activity of insulin-secreting pancreatic islets. This study was designed to systematically examine the direct effects of metformin by measuring insulin secretion and the kinetics of the calcium response to glucose stimulation in isolated mouse islets using varying concentrations (20 M, 200 M, and 1 mM) and durations (~1, 2, and 3 days) of metformin exposure.

Morphological caste studies in the neotropical swarm-founding Polistinae wasp Angiopolybia pallens (Lepeletier) (Hymenoptera: Vespidae).

Neotropical swarm-founding wasps present polygynic colonies and a great variation in relation to caste differentiation, ranging from species in which queens and workers are similar in shape and size to those where variation in shape and size is conspicuous. Canonical discriminant analysis and Bonferroni t-test analysis on morphometric data collected from eight body parts of specimens from nine colonies of Angiopolybia pallens (Lepeletier) were undertaken as a step towards to a better understanding on caste differenciation in Epiponini. All specimens were dissected to verify the ovary developmental stage, and the spermatheca was removed to check for the mating status.

Pretranslational regulation of albumin synthesis in tumor-bearing mice. The role of anorexia and undernutrition.

Hepatic albumin synthesis, serum albumin turnover, and hepatic albumin messenger RNA (mRNA) content were evaluated in mice bearing a transplantable low differentiated tumor (MCG 101). Results obtained on tumor-bearing mice were compared with results obtained from non-tumor-bearing animals that were either freely fed, food restricted so that their body composition was similar to tumor-bearing animals (pair-weighed), fed a protein-free diet for 5 days, or fasted for 48 hours. Tumor-bearing animals became hypoalbuminemic (33 +/- 5 vs.

Skeletal muscle microcirculation and oxygenation in experimental intestinal shock: A study on the efficacy of different plasma substitutes.

Shock was induced in 60 dogs by exteriorization of the small intestine for three hours. The relative effectiveness of various hemodiluting agents on the microcirculation was measured as skeletal muscle capillary blood flow (QXe) and capillary permeability (P) surface area (S) for plasma (PSp), as calculated from the clearances of two locally injected isotopes, 133 Xenon and 131 Iodide. Skeletal muscle oxygen tension (Pm(2) was measured with a tissue PO2 electrode.

Outcome of repeated renal regrafting.

Fifteen patients underwent renal transplantation 4 and in one case 5 times. 7/15 grafts (47%) survived more than one year. The one year graft loss due to rejection was 40%.

Steroids and rejection treatment in the Gothenburg transplant programme.

Our experience from the Gothenburg material indicates that the graft prognosis is highly dependent on pretransplant blood transfusions, to a lesser degree on avoidance of two mismatches for the HLA-B-locus and, not the least, on the use of methylprednisolone antirejection therapy. It seems that a rather moderate dosage of methylprednisolone allows us to prolong and repeat the courses according to individual needs, and this may be the main reason for the significantly improved graft function at one year. The experiences gained and the lessons learned from the transplant programme in Gothenburg have resulted in 70% of the uraemic patients in the Gothenburg region being alive with functioning renal transplants.

Pretreatment with blood transfusions in primary kidney transplantation.

Since 1977 a deliberate pretransplant transfusion protocol consisting of two units of leucocyte poor blood given minimum 6 weeks prior to transplantation was applied to earlier not transfused recipients of primary renal transplants in Gothenburg. Graft loss due to rejection at 6 months was 17% and 8% in cadaver and one shared HLA-haplotype living donor recipients, respectively. These results were very much superior to those earlier obtained in not transfused recipients in this centre.

Active treatment of uremia in the city of Göteborg 1966-1977.

137 patients were actively treated because of chronic uremia, during 1966 to 1977 in the city of Göteborg. One year patient survival increased from 51% (1966 to 1968) to 81% (1975 to 1977). Peritoneal dialysis decreased as the initial mode of treatment, and only 3% of the patients started dialysis treatment with this mode of therapy in the last 3-year period.

Oxygen consumption and recovery from surgical shock in rats: a comparison of the efficacy of different plasma substitutes.

Shock was induced in 537 rats by exteriorization of the intestines and occlusion of the superior mesenteric circulation for 1 hour. After 1 hour of this intestinal ischemia shock, oxygen consumption (VO2) decreased to half of the preexperimental values. When no infusion was given, the survival rate at 24 hours was 22%; this was correlated with the degree of restoration of VO2 at 1 hour after shock.

Hemodilution and oxygen transport to tissue in shock.

Shock was induced in sixty dogs by laparotomy, splenectomy and exteriorization of the small intestine for three hours. Resuscitation following different plasma substitutes was assessed by measuring hemodynamic parameters (mean arterial blood pressure, plasma volume, oxygen consumption, cardiac output and hematocrit). To justify a comparison, the colloids (albumin, ACD-plasma, dextran 40, dextran 70, gelatine) were given at the same concentration and dose (3.

The general and local response to injury related to complement activation.

Injury can activate the complement system as well in vivo as in vitro. This activation might contribute to some of the phenomena seen after large injuries. Such general effects as fall in blood pressure, impaired ability to oxygenate blood and local effects such as accumulation of granulocytes and oedema formation might be influenced by complement activity.

Successful kidney transplantation in a man with Dacron "trouser" prosthesis.

The case history of a male patient, 62 years old, in preterminal uremia at transplantation with a cadaveric kidney is described. Twelve years before the transplantation he was operated on because of an aortic aneurysm where the abdominal aorta and both iliac arteries were substituted with a Dacron prosthesis. The kidney was anastomosed to this vessel substitute and functioned excellently for more than five years and the patient was completely rehabilitated.