Improving perinatal outcome in rural Missouri as reflected by a lowering of the perinatal mortality rate is a realistic and achievable goal for the state. The authors present information and data with suggestions for reaching this goal.
View Article and Find Full Text PDFSix infants with total anomalous pulmonary venous connection below the diaphragm had correction by modification of conventional surgical technique. Catheterization revealed the confluence of the pulmonary veins draining into a descending vein below the diaphragm. Symptoms of pulmonary venous hypertension and low cardiac output were typical.
View Article and Find Full Text PDFPrenatal testing for Down Syndrome, the most common human malformation, is possible through three techniques: analysis of historical risk factors, ultrasonography, and evaluation of maternal serum alpha-fetoprotein levels. The authors describe these current screening techniques.
View Article and Find Full Text PDFFour cases of hypertrophic obstructive cardiomyopathy diagnosed on clinical, phonomechanographic, echocardiographic and haemodynamic criteria progressing to dilated cardiomyopathy are reported. This evolution was observed over a number of years (up to 20 years) and was accompanied by a clinical aggravation in all cases with 2 deaths and atrial fibrillation in 3 of the 4 cases. The signs of intraventricular obstruction [systolic murmur, bulge on the carotid pulse tracing, systolic anterior motion of the mitral valve (SAM) and intraventricular pressure gradient] disappeared as the left heart chambers dilated with a reduction in ventricular wall motion and parietal thinning but no change in myocardial mass.
View Article and Find Full Text PDFThe performance of the serum complement fixation (CF) test was compared with that of a serum agar gel immunodiffusion (AGID) test on 74 subclinically infected and 154 uninfected cattle in 6 commercial midwestern dairy herds with Mycobacterium paratuberculosis infection and on 30 cattle in a herd that was free of infection. Infection status of cattle within herds was established by performance of a series of 3 or more fecal cultures and of ileocecal lymph node cultures of culled cattle. In cattle with subclinical infection detected by culturing, the sensitivity estimates of the CF and AGID tests were 10.
View Article and Find Full Text PDFAJR Am J Roentgenol
March 1990
Detailed neurologic studies, high-field-strength MR imaging, and CT scanning were performed preoperatively in 53 patients with intractable complex partial seizures who underwent surgical treatment for epilepsy. Macroscopic structural (tumoral or vascular) lesions were found in 28% of patients. The remainder had pathologic findings consistent with mesial temporal gliosis.
View Article and Find Full Text PDFChinese health care was examined by three American nurses who visited China between 1986 and 1988. A thorough discussion of women's health care as it was presented to the authors is provided. Each author found the experience invaluable to her understanding of the world and the vast differences, as well as commonalities, between health care in the United States and health care in China.
View Article and Find Full Text PDFTo determine if the severity of osteoporosis and its resultant hyperkyphosis cause measurable impairment of lung function, 74 women referred for osteoporosis evaluation underwent pulmonary function testing. Women with thoracic wedge compression fractures secondary to osteoporosis had significantly lower percent predicted FVC than did those without fractures. In hierarchical regression analysis, after controlling for age and arm span, there was a significant effect on FVC of the degree of hyperkyphosis as measured by Cobb's angle (increment in R2 = 0.
View Article and Find Full Text PDFA model community-based comprehensive agricultural occupational health and safety service program has been implemented in Iowa. The functional center of coordination is based in the College of Medicine at the University of Iowa. The community-based hub of the service is the community hospital, where the majority of the direct client services originate.
View Article and Find Full Text PDFChemotactic factors and phorbol esters may act synergistically to evoke neutrophil responses, but the mechanism of such interaction is not entirely clear. We investigated the combined effects of the chemotactic peptide n-formyl-methionyl-leucyl-phenylalanine (FMLP) and phorbol myristate acetate (PMA) on protein kinase C (PKC) activity in human neutrophils. FMLP had little effect on the sharp decrease in cytosolic PKC activity induced by PMA.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
March 1990
Detailed neurologic studies, high-field-strength MR imaging, and CT scanning were performed preoperatively in 53 patients with intractable complex partial seizures who underwent surgical treatment for epilepsy. Macroscopic structural (tumoral or vascular) lesions were found in 28% of patients. The remainder had pathologic findings consistent with mesial temporal gliosis.
View Article and Find Full Text PDFPlatelet-activating factor is a potent proinflammatory lipid mediator which directly stimulates neutrophil chemotaxis, degranulation, aggregation, and superoxide radical (O2-) production. PAF also modifies or 'primes' neutrophil responses to other agents. Although a relatively weak direct oxidative agonist, PAF markedly enhances O2- release evoked by phorbol myristate acetate (PMA) and the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP), increasing the maximal rate of O2- production by a calcium-dependent mechanism.
View Article and Find Full Text PDFAnyone who submits a manuscript for peer review is at high risk for experiencing rejection. Dealing with rejection is not easy. Sometimes major revisions, based on the reviewers' comments, can help salvage the manuscript.
View Article and Find Full Text PDFJ Am Acad Nurse Pract
May 1990
A national study to determine how obstetric/gynecologic nurse practitioners (OGNPs) make practice change was conducted. A random sample of 1000 currently certified OGNPs was surveyed. Results indicated that continuing education meetings were primary sources of practice change information.
View Article and Find Full Text PDFPulmonary artery banding is facilitated by simultaneously measuring the pressure above and below the band. This can be accomplished with a commercially available double-lumen central venous pressure monitoring catheter. This catheter is inserted through the outflow tract of the right ventricle and positioned so that the band will be between the two lumens.
View Article and Find Full Text PDFConcurrent bacteriologic culture of feces and agar gel immunodiffusion (AGID) testing was performed on all cows and bred heifers over 14 months old in 10 dairy herds during a 32-month period to determine the effectiveness of the AGID test for the detection of subclinical paratuberculosis. Herds were sampled 5 times and, when possible, culled animals were tested again at slaughter. During 5 herd-wide samplings, Mycobacterium paratuberculosis was isolated from 139 fecal specimens obtained from 109 cattle.
View Article and Find Full Text PDFNeutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfusion canine model. Closed-chest dogs were subjected to 90 minutes of left anterior descending artery occlusion followed by 24 hours of reperfusion.
View Article and Find Full Text PDFFive doctoral faculty members were randomly selected from each faculty group of 35 doctoral programs in nursing to identify which nursing journals they read most often and which nursing journals they assign most often to doctoral students. Five nursing journals were consistently ranked 1-4 as being read and assigned most often. These journals are: Nursing Research, Advances in Nursing Science, IMAGE: Journal of Nursing Scholarship, Research in Nursing and Health, and Western Journal of Nursing Research.
View Article and Find Full Text PDFWe have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated, phospholipid-dependent protein kinase (protein kinase c, PKC) in human neutrophils, we investigated the role of PAF in modifying PMA-induced PKC activation/translocation. Protein kinase activity was measured as the incorporation of 32P from gamma-32P-ATP into histone H1 induced by enzyme in cytosolic and particulate fractions from sonicated human neutrophils.
View Article and Find Full Text PDFA review and analysis of Reva Rubin's major publications is presented. Rubin's contributions to maternity nursing are acknowledged and questions concerning the applicability of Rubin's theories to current practice are raised. Nursing implications are drawn for contemporary nursing practice, and areas for future research are identified.
View Article and Find Full Text PDFArch Mal Coeur Vaiss
April 1988
None of the medical treatments of hypertrophic cardiomyopathy is perfect. In the present study conducted on 11 patients with hypertrophic cardiomyopathy in whom the usual treatments were either ineffective or badly tolerated, the haemodynamic effects of propafenone administered intravenously were investigated. The drug was injected centrally in doses of 2 mg/kg over 10 minutes, then by continuous intravenous infusion of 1.
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