Publications by authors named "G. Orhun"
Objectives: Vomiting is frequently observed in cats after dexmedetomidine administration. This study aimed to compare the efficacy of different antiemetics in preventing vomiting in cats after dexmedetomidine administration.
Methods: Sixty-four cats were randomly allocated to receive saline solution (0.
Background: Pulse oximetry is a valuable tool for monitoring animals during anesthesia and assessing the adequacy of administered oxygen therapy.
Aims: To compare the pulse oximeter readings obtained by the Garmin Fenix 5X plus (GF5Xp) smartwatch and transmittance pulse oximetry (TPO) in anesthetized dogs.
Methods: Twelve clinical canine patients requiring anesthesia for castration were prospectively enrolled in this study.
A Different Approach to Toxic Epidermal Necrolysis: Cytokine Filter.
Turk J Anaesthesiol Reanim
August 2021
Toxic epidermal necrolysis (TEN) is a potentially life-threatening dermatologic disorder that erythema and exfoliation of the skin involve more than 30% of the body surface and usually drug related. A 68-year-old male patient who was admitted to the emergency department with the complaint of extensive bullous lesions on his skin was followed up in the intensive care unit (ICU) with the diagnosis of TEN. He had been on multiple anti-inflammatory, antibiotic and analgesic treatment for approximately 20 days due to respiratory tract infection and gout.
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- Candida auris is a significant fungal pathogen causing hospital infections, known for its antifungal resistance and misidentification by commercial testing systems.
- It has been associated with higher mortality rates, especially in immunocompromised patients, despite having lower virulence than Candida albicans.
- The text presents Turkey's first case of COVID-19 related C. auris infection in a 71-year-old male with multiple health issues, emphasizing the increased occurrence of this fungus in COVID-19 patients.
Objectives: To evaluate the effect of adjunct treatment with Octagam, an intravenous immunoglobulin (IVIG) product, on clinical outcomes and biomarkers in critically ill COVID-19 patients.
Methods: Data from a single center was analyzed retrospectively. Patients had received preliminary standard intensive care (SIC) according to a local treatment algorithm, either alone or along with IVIG 5% at 30 g/day for 5 days.
Article Synopsis
- IV immunoglobulin (IVIg) treatment helps improve behavior and survival in rats with sepsis by preventing brain damage.
- Researchers tested different groups of rats with various treatments to see how these treatments affect brain and blood health over time.
- The results showed that IVIg treatment lowers harmful proteins in the brain and reduces brain cell death, helping the rats recover from sepsis better.
Article Synopsis
- Sepsis negatively affects capillary function and oxygen delivery, potentially worsening patient outcomes.
- Lower levels of immunoglobulin G2 do not contribute to severe flu complications, suggesting other factors may play a role in flu severity.
- New research indicates that intravenous immunoglobulin may provide brain protection during sepsis by blocking harmful immune responses such as complement activation and apoptosis. *
Article Synopsis
- There is a serious problem in hospitals, especially in the intensive care units (ICUs), with dangerous germs that are hard to treat because they resist many medicines, called multidrug-resistant (MDR) microorganisms.
- In a study, researchers looked at how many patients in the ICU had these germs living in their bodies, particularly in their rectums, which can lead to infections.
- They found that out of 80 patients, 46% had at least one of these harmful germs, with the most common ones being certain types of bacteria that can cause severe infections.
Background: We aim to demonstrate behavioral alterations in a sepsis model using intravenous (IV) immunoglobulin G (IgG) and immunoglobulins enriched with IgA and IgM (IgGAM).
Methods: We divided 48 Wistar albino rats into five groups: control group, sham-operated group (only antibiotic treatment), cecal ligation and puncture (CLP) group (CLP plus antibiotic treatment), IgG group (250 mg/kg IV IgG) and IgGAM group (250 mg/kg IV IgGAM). Intravenous immunoglobulins were given 5 min after the CLP procedure.
Background: We aimed to test the methylene blue (MB) as a dye and also to test its antioxidant activities in devascularization-induced liver injury.
Methods: Twenty rats weighing 240-280 g were randomly divided into two groups, each containing 10 rats. High-grade liver injury was induced by using a pair of long pliers with blades.