Publications by authors named "G-Z Qin"
Article Synopsis
- Peanuts grown in saline alkali soil face challenges from both drought stress and salt, prompting a study on the HY25 peanut variety to understand their combined effects on growth and yield.
- The study found that short-term drought and salt stress significantly reduced various growth metrics, such as plant height, branch length, leaf area, and photosynthetic efficiency, ultimately leading to lower peanut yields.
- The sensitivity to drought stress varies at different growth stages, with the 40th day after planting being particularly critical, indicating that avoiding drought, especially early on, is essential for maximizing peanut yield in these challenging conditions.*
Article Synopsis
- Chronic limb-threatening ischemia is a serious condition due to peripheral artery disease, but current treatment options are limited by the absence of suitable stents.
- Researchers have developed a long, biodegradable stent (up to 118 mm) using a metal-polymer composite, which features a special coating method to enhance performance.
- Successful implantation of this stent in human patients after preclinical testing indicates its potential for effective use in treating ischemic conditions over the long term.
Background: NDRG-1 (N-myc downstream-regulated gene 1) is a member of NDRG family that plays essential roles in cell differentiation, proliferation, and stress responses. Although the expression of NDRG1 is regulated by fluid shear stress, its roles in vascular biology remain poorly understood. The purpose of the study is to determine the functional significance of NDRG1 in vascular inflammation and remodeling.
View Article and Find Full Text PDFGlobal Burden and Trends in Incidence, Mortality, and Disability of Stomach Cancer From 1990 to 2017.
Clin Transl Gastroenterol
October 2021
Introduction: Stomach cancer is a serious global public health problem. The current burden of stomach cancer and its trends across time and location need to be understood to develop effective preventive strategies.
Methods: Data were obtained from the Global Burden of Disease study.
Background And Purpose: Cerebral endothelial cells (CECs) and axons of neurons interact to maintain vascular and neuronal homeostasis and axonal remodeling in normal and ischemic brain, respectively. However, the role of exosomes in the interaction of CECs and axons in brain under normal conditions and after stroke is unknown.
Methods: Exosomes were isolated from CECs of nonischemic rats and is chemic rats (nCEC-exos and isCEC-exos), respectively.
Article Synopsis
- SARS-CoV-2 is the virus responsible for the COVID-19 pandemic, and currently, there is no vaccine to combat it.
- Researchers have developed a synthetic DNA vaccine called INO-4800, targeting the Spike protein of SARS-CoV-2, building on previous work with the MERS coronavirus.
- Initial tests in mice and guinea pigs show that INO-4800 generates strong immune responses, including neutralizing antibodies, marking it as a potential candidate for further development as a COVID-19 vaccine.
We aimed to investigate the relationship of time-averaged on-treatment systolic blood pressure (SBP) with the risk of first stroke in the CSPPT (China Stroke Primary Prevention Trial). A post hoc analysis was conducted using data from 17 720 hypertensive adults without cardiovascular disease, diabetes mellitus, and renal function decline from the CSPPT, a randomized double-blind controlled trial. The primary outcome was first stroke.
View Article and Find Full Text PDFBackground: Conflicting evidence exists regarding whether reduced estimated glomerular filtration rate (eGFR) and proteinuria are independent risk factors for stroke and its subtypes in hypertensive patients. This study investigated the association of these renal measures with first incident stroke in adults under treatment for hypertension in China.
Methods And Results: The study included 19 599 adults aged 45 to 75 years who participated in the China Stroke Primary Prevention Trial.
Background And Purpose: Early hematoma growth is not uncommon in patients with intracerebral hemorrhage and is an independent predictor of poor functional outcome. The purpose of our study was to report and validate the use of our newly identified computed tomographic (CT) blend sign in predicting early hematoma growth.
Methods: Patients with intracerebral hemorrhage who underwent baseline CT scan within 6 hours after onset of symptoms were included.
Pheochromocytoma (PHEO) is a rare but potentially lethal neuroendocrine tumor arising from catecholamine-producing chromaffin cells. Especially for metastatic PHEO, the availability of animal models is essential for developing novel therapies. For evaluating therapeutic outcome in rodent PHEO models, reliable quantification of multiple organ lesions depends on dedicated small-animal in vivo imaging, which is still challenging and only available at specialized research facilities.
View Article and Find Full Text PDFEukaryotic cytochrome c oxidase (CcO) and homologous prokaryotic forms of Rhodobacter and Paraccocus differ in the EPR spectrum of heme a. It was noted that a histidine ligand of heme a (H102) is hydrogen bonded to serine in Rhodobacter (S44) and Paraccocus CcOs, in contrast to glycine in the bovine enzyme. Mutation of S44 to glycine shifts the heme a EPR signal from g(z) = 2.
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