Publications by authors named "G van Loon"
Article Synopsis
- The study focused on identifying diseases and risk factors leading to death in hospitalized neonatal foals.
- Sepsis was the most common disease found, significantly increasing mortality risk, with a case fatality rate of 33.3%.
- Key risk factors included comatose state, high L-lactate levels, and increased serum amyloid A, which could help veterinarians make informed decisions during treatment.
Article Synopsis
- The study investigated the use of ablation index-guided radiofrequency catheter ablation (RFCA) to treat atrial tachycardia (AT) in horses, focusing on the caudal vena cava, a common problem area.
- Ten horses with sustained AT underwent three-dimensional electro-anatomical mapping and RFCA, achieving successful isolation of the caudal vena cava and restoring normal heart rhythm in all cases.
- Follow-up showed no recurrence of AT in the horses studied, indicating the method's effectiveness and feasibility for long-term treatment.
Article Synopsis
- The study investigates how renal artery stenosis (RAS) affects blood flow and renin release in a pig model, particularly when there is significant stenosis on the opposite kidney side.
- Researchers measured kidney pressure and blood flow while gradually blocking the renal artery to understand how these changes impact renin secretion.
- Findings revealed that a 25% reduction in renal perfusion pressure significantly reduced blood flow and increased renin release, especially when there was already significant stenosis in the contralateral kidney.
Background: MicroRNA (miRNA) has previously been used as a biomarker for cardiac disease in humans and dogs, however, studies in horses are not yet available.
Objectives: To determine if adult horses with moderate or severe mitral valve regurgitation have a different serum miRNA expression profile compared to healthy controls.
Study Design: Retrospective cross-sectional.
Sustained atrial tachycardia at an atrial rate of 191/min on the surface ECG was detected in a 6-year-old Warmblood mare. The vectorcardiogram obtained from a 12-lead ECG suggested a caudo-dorsal right atrial origin of the arrhythmia. Impedance-based three-dimensional electro-anatomical mapping, using the EnSite™ Precision Cardiac Mapping System revealed a clockwise macro-reentry around a line of conduction block in the caudomedial right atrium.
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