Examination of effects of indoor fires on building structures and people.

The scientific study of the harmful effects of indoor fires on building structures and on the environment is a top issue today. Indoor fires frequently occur all over the world. The goal of our research is to examine the effects of an average room fire on the survival possibility of a trapped person and on the building structure, taking into account features of the Eastern European architecture.

The fate of p-bromo-methylamphetamine (V-111) in the body.

The fate of p-bromo-methylamphetamine (V-111) in the body was studied by means of its radioactive labelled forms in mouse and rat experiments. It was found with the whole body autoradiographic method and liquid-scintillation measurements that the compound is rapidly absorbed by whatever routes of administration and it is rapidly taken up by the tissues from the blood stream. In the central nervous system, it reaches higher concentration than methyl-amphetamine and it leaves the central nervous system more slowly.

Pharmacokinetic data on tritium labelled ethyl apovincaminate.

Absorption, tissue distribution and excretion of tritium labelled ethyl apovincaminate (RGH-4405, Cavinton) were studied. Both oral and i.p.

Absorption, distribution and elimination of azidomorphine and related substances.

The absorption, distribution and elimination of 14C- and 3H-azidomorphine, 3H-14-OH-azidomorphine, 14C- and 3H-azidocodeine and 3H-azidoethylmorphine were studied in comparison to 14-C-morphine. Whole body autoradiography of pregnant mice, quantitative estimations of tissue radioactivity in male mice, brain autoradiography, subcellular distribution in rat brain and elimination studies in rats were performed. Azidomorphine and morphine are absorbed from the gastrointestinal tract at the same rate but the absorption of 14-OH-azidomorphine, azidocodeine and azidoethylmorphine exceeds that of the formers.