Publications by authors named "G Zhunussova"

Article Synopsis
  • - The research focused on creating a specialized sports food (a milk-fruit bar) designed to enhance the medical and nutritional needs of athletes, particularly in martial arts and endurance sports like triathlons and pentathlon.
  • - The bar was made from a blend of dry goat milk, whey, fruit, grains, plant and animal proteins, vitamins, and beneficial bacteria, aiming to improve athletes' performance and recovery.
  • - After 21 days of consumption, athletes consuming the bar showed significant reductions in cholesterol levels (up to 18.9%) and lactate levels (up to 28.3%), indicating improved metabolic responses compared to a control group taking placebo bars.
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Article Synopsis
  • * Findings show high genetic diversity in the Kazakh Tobet, classified into seven distinct genetic clusters, indicating its complex genetics.
  • * The research suggests shared ancestry with breeds like the Central Asian Shepherd Dog and Turkish Akbash, and highlights the breed's ancient origins, providing a foundation for preservation and international recognition.
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Background: Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition commonly linked with Graves' disease (GD), characterized by orbital tissue inflammation and fibrosis. It is hypothesized that gene polymorphisms may influence production of the IL-17 and IL-38 cytokines, thereby impacting TAO development and progression. This study focused on investigating the gene polymorphisms of IL-17 (rs9463772 C/T in IL17F) and IL-38 (rs3811058 C/T, rs7570267 A/G in IL1F10) in patients with GD.

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Background: Tuberculosis (TB) is a major public health emergency in many countries, including Kazakhstan. Despite the decline in the incidence rate and having one of the highest treatment effectiveness in the world, the incidence rate of TB remains high in Kazakhstan. Social and environmental factors along with host genetics contribute to pulmonary tuberculosis (PTB) incidence.

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Background: Tuberculosis (TB) and vitamin D deficiency remain major public health problems in Kazakhstan. Due to the high incidence of pulmonary tuberculosis in the country and based on the importance of vitamin D in the modulation of the immune response and the association of its deficiency with many health conditions, the aim of our research was to study the vitamin D status, VDR and TLR gene polymorphisms, and pulmonary tuberculosis epidemiology in Kazakhstan.

Methods: A case-control study included 411 individuals diagnosed with pulmonary TB and 686 controls with no family history of pulmonary tuberculosis.

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