Publications by authors named "G Zaninotto"

Fundoplication is a durable, effective, and well-accepted treatment for gastroesophageal reflux disease. Nonetheless, troublesome postoperative symptoms do occasionally occur with management varying widely among centers. In an attempt to standardize definition and management of postfundoplication symptoms, a panel of international experts convened by the Guidelines Committee of the International Society for Diseases of the Esophagus devised a list of 33 statements across 5 domains through a Delphi approach, with at least 80% agreement to establish consensus.

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Background: Oesophageal cancer, in particular adenocarcinoma, has a strong male predominance. However, the impact of patient sex on operative and oncologic outcomes and recovery of health-related quality of life is poorly documented, and was the focus of this large multicentre cohort study.

Methods: All consecutive patients who underwent oncological oesophagectomy from 2009 to 2015 in the 20 European iNvestigation of SUrveillance after Resection for Esophageal cancer study group centres were assessed.

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Article Synopsis
  • Recent advancements in diagnostics and therapies for esophageal achalasia have improved understanding of this rare disorder, but further research is still necessary.
  • The review highlights five key areas needing attention: pathogenesis, functional imaging in diagnosis, treatment outcomes, management of persistent chest pain, and the potential benefit of long-term follow-up for patients.
  • Ongoing questions include the immune-genetic factors affecting achalasia, establishing a clear definition of treatment success, using neuromodulators for pain management, and identifying patients at risk for cancer.
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Achalasia is a rare esophageal disorder characterized by abnormal esophageal motility and swallowing difficulties. Pain and/or spasms often persist or recur despite effective relief of the obstruction. A survey by UK charity 'Achalasia Action' highlighted treatments for achalasia pain/spasms as a key research priority.

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