Publications by authors named "G Zang"

Article Synopsis
  • - LWIR cameras are vital for various applications but require advanced lens designs that are broad in bandwidth, lightweight, compact, and cost-effective due to high-performance demands.
  • - The proposed method utilizes inverse design for LWIR hybrid metalenses, focusing on correcting aberrations while achieving a large field of view (30°) and a broad bandwidth (8 to 14 μm) for thermal imaging.
  • - This innovative design significantly improves upon existing technologies by offering enhanced field of view, efficiency, and a remarkably compact optical path length of just 13.6 mm, enabling more effective imaging and sensing applications.
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Viruses can infiltrate the central nervous system and contribute to depression, which may include alterations in dopamine (DA) metabolism triggered by immune responses though the specific mechanisms involved remain unclear. Here, an electrochemical system to realize the real-time dynamic monitoring of DA with high sensitivity is proposed and it is demonstrated that the viral simulator polyinosinic-polycytidylic acid (poly(I:C)) can inhibit the release of DA (from 5.595 to 0.

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Article Synopsis
  • The study focuses on the importance of carefully managing reactive oxygen species (ROS) to effectively treat infected wounds, as too much ROS can lead to inflammation and worsen infections.
  • A new "one for all" self-adaptive integrated photodynamic therapy (PDT) and antioxidant model using a gelatin-hyaluronic acid hydrogel embedded with Se-modified cerium dioxide nanoparticles is proposed to balance ROS production and scavenging.
  • Experiments showed that this innovative approach not only helps shift the immune response from inflammation to healing but also enhances wound repair processes by promoting blood vessel formation through specific cellular pathways.
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TGFβ potently modifies the extracellular matrix (ECM), which is thought to favor tumor cell invasion. However, the mechanism whereby the cancer cells employ the ECM proteins to facilitate their motility is largely unknown. In this study we used RNA-seq and proteomic analysis to examine the proteins secreted by castration-resistant prostate cancer (CRPC) cells upon TGFβ treatment and found that thrombospondin 1 (THBS1) was observed to be one of the predominant proteins.

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Without intervention, the natural wound healing process can often result in scarring, which can have detrimental effects on both the physical and mental well-being of patients. Therefore, it is crucial to develop biomaterials that can promote healing without scarring. Regulating the Yes-associated protein-1/PDZ-binding motif (YAP/TAZ) signaling pathway is possible to reduce excessive fibrosis of fibroblasts and proliferation of vascular endothelial cells, ultimately impacting scar formation.

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