Publications by authors named "G Yalcin Sezen"
Background: Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. Stem cell transplantation has evolved as a novel treatment modality in the management of TBI, as it has the potential to arrest the degeneration and promote regeneration of new cells in the brain. Wharton's Jelly-derived mesenchymal stem cells (WJ-MSCs) have recently shown beneficial effects in the functional recovery of neurological deficits.
View Article and Find Full Text PDFBackground: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in the adult as well as in the neonate, with limited options for treatment and significant dysfunctionality.
Aim: To investigate the safety and preliminary efficacy of allogeneic mesenchymal stem cells (MSCs) in HIE patients.
Methods: Patients who had HIE for at least 6 mo along with significant dysfunction and disability were included.
Article Synopsis
- The study focuses on a 29-year-old male patient with traumatic brain injury (TBI) from a vehicle accident, who received stem cell transplantation (SCT) to address ongoing deficiencies.
- The treatment involved six doses of Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) delivered through intrathecal, intramuscular, and intravenous routes over six months.
- Results showed improvements in speech, cognition, memory, and fine motor skills, with no major side effects, highlighting SCT's potential as a treatment for TBI.
Aim: To elucidate the characteristics of kyphoplasty in correlation with spinal metastasis.
Material And Methods: Data of patients treated by kyphoplasty between January 2017 and December 2019 were reviewed retrospectively. Preoperative prophylactic antibiotics and low-molecular-weight heparin injections were performed.