Multiomics Analysis Reveals Key Targeted Metabolic Pathways Underlying the Hormesis and Detrimental Effects of Enrofloxacin on Rice Plants.

Fluoroquinolone antibiotic enrofloxacin (ENR) is frequently detected in agricultural environments. The hormesis and detrimental effects of ENR on crops have been extensively observed. However, the molecular mechanisms underlying these crops' responses to ENR remain limited.

How Should We Use Hyaluronidase for Dissolving Hyaluronic Acid Fillers?

Background: Hyaluronic acid (HA) fillers are commonly used in esthetic medicine for facial contouring and rejuvenation. However, complications such as overcorrection, vascular occlusion, and irregular filler distribution necessitate the use of hyaluronidase to dissolve the fillers. This study aimed to evaluate the efficacy of hyaluronidase in degrading different types of HA fillers and provide clinical guidelines for its use based on filler type, dosage, and application techniques.

Why Does an "Avatar Nose" Appear After Dermal Filler Injection? Insights From a Cadaveric Study on the Nasofrontal Ligament.

Background: Nonsurgical rhinoplasty (NSR) with dermal fillers has gained popularity because of its immediate and visible results, minimal downtime, and long-lasting effects. However, complications such as filler migration can lead to the development of the "Avatar nose," a condition where the nose appears unnaturally wide and bulbous in the nasion area, disrupting facial harmony. This phenomenon is often exacerbated by the presence of a taut nasofrontal ligament, which tethers the periosteum to the dermal layer and influences nasal contour.

Differential expression of osteoblast-like cells on self-organized titanium dioxide nanotubes.

Background/purpose: Titanium dioxide nanotube (TNT) structures have been shown to enhance the early osseointegration of dental implants. Nevertheless, the optimal nanotube diameter for promoting osteogenesis remains unclear due to variations in cell types and manufacture of nanotubes. This study aimed to evaluate the differences in MC3T3-E1 and Saos-2 cells behavior on nanotubes of varying diameters.

Anatomic-Based Diagnosis and Filler Injection Techniques: Chin Augmentation and Jawline Contouring.

Chin augmentation and jawline contouring have emerged as significant procedures in aesthetic medicine, addressing both structural and age-related changes in the lower face. This review explores anatomic-based diagnosis and filler injection techniques for these treatments. Ethnic variations in facial structure necessitate different approaches, with Western patients often seeking jawline definition, while Asian patients frequently require chin projection.