Publications by authors named "G Wylie"
Persistent cognitive fatigue (CF) is the most reported symptom in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), but little is known about its underlying neural basis. This pilot study examined fMRI brain activation patterns during a fatiguing task in those with and without PASC. We hypothesized that individuals with PASC would show changes in CF-related brain activation within fatigue network.
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- Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome is an autosomal-dominant genetic disorder linked to mutations in the fumarate hydratase (FH) gene, leading to renal cell carcinoma, and benign tumors like leiomyomas.
- A case study describes a man in his 30s who developed a grade 1 leiomyosarcoma after having a kidney removed due to fumarate-deficient RCC, and genetic testing confirmed an FH gene variant.
- This case highlights the rarity of leiomyosarcoma in HLRCC patients and emphasizes the importance of histopathological analysis and monitoring for early intervention.
Deficits in memory performance have been linked to a wide range of neurological and neuropsychiatric conditions. While many studies have assessed the memory impacts of individual conditions, this study considers a broader perspective by evaluating how memory recall is differentially associated with nine common neuropsychiatric conditions using data drawn from 55 international studies, aggregating 15,883 unique participants aged 15-90. The effects of dementia, mild cognitive impairment, Parkinson's disease, traumatic brain injury, stroke, depression, attention-deficit/hyperactivity disorder (ADHD), schizophrenia, and bipolar disorder on immediate, short-, and long-delay verbal learning and memory (VLM) scores were estimated relative to matched healthy individuals.
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