Publications by authors named "G Wuerzner"

We report a patient with autonomic dysfunction following acute SARS-CoV-2 infection, presenting progressively worsening severe orthostatic hypotension to the point where she could no longer sit or stand. The patient experienced a delay in diagnosis after an initial misdiagnosis of a functional neurological disorder. Persistent orthostatic symptoms prompted us to re-examine the diagnosis and explore other diagnostic tools, which ultimately allowed us to identify and treat severe immune-mediated orthostatic hypotension (OH).

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The major clinical studies in 2024 reviewed in this manuscript will focus on blood pressure measurement, the effect of coffee on the latter, its follow-up in the postpartum period, blood pressure targets for patients at high cardiovascular risk, particularly those with diabetes, and the late onset of primary aldosteronism after a negative initial confirmation test.

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Article Synopsis
  • A study analyzed the prevalence and treatment of hypertension (HTN) in solid organ transplant recipients over five years, focusing on kidney, heart, lung, and liver transplants.
  • The study found high rates of HTN, with prevalence ranging from 61.8% to 90.4% at different time points, and identified significant cases of uncontrolled HTN particularly in kidney, liver, and lung transplant recipients.
  • Uncontrolled HTN poses a serious risk after transplantation, emphasizing the need for better management strategies, especially among liver and lung transplant patients who may not have pre-existing cardiovascular problems.
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An inadequate diet, either in its composition, preparation, or even in the processing of its components, plays a crucial role in the development of cardiovascular diseases, particularly through its effects on blood pressure, lipid and carbohydrate metabolism, as well as body weight. Non-pharmacological measures are an integral part of the prevention and management of cardiovascular risk factors, even before the introduction of specific medication. Based on literature, it is established that a so-called "healthy" diet has clear and well-demonstrated benefits, especially in early stages after diagnostic.

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Aldosterone is a steroid hormone playing a key role in arterial hypertension physiopathology. In case of inappropriate secretion, it has a detrimental action on the kidney and cardiovascular system and therefore constitutes an interesting therapeutic target for several diseases. Recent progress allowed to expand the therapeutic arsenal for physician practitioner and new promising drugs will probably appear on the market the next few years.

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